Comprehensive scRNA-seq analyses resolve the major cell types in the human IVD To determine the cellular composition of the human IVD, we employed droplet-based single-cell transcriptomic profiling (10X Genomics Chromium System) of cells from the NP, AF, and CEP from five healthy human IVDs (Pf...
Single-cell RNA-sequencing analysis to quantify the RNA molecules in individual cells has become popular, as it can obtain a large amount of information from each experiment. We introduce UniverSC ( https://github.com/minoda-lab/universc ), a universal s
Neuroendocrine tumours (NETs), which arise from specialized secretory cells scattered throughout the neuroendocrine system, present with a wide array of clinical symptoms and manifestations. The rising number of NET diagnoses is not solely attributable to heightened awareness or advancements in diagnostic ...
2.1.1 Part 1 Section 2.2, Application Conformance 2.1.2 Part 1 Section 8.6, PresentationML 2.1.3 Part 1 Section 9, Packages 2.1.4 Part 1 Section 11, WordprocessingML 2.1.5 Part 1 Section 11.3, Part Summary 2.1.6 Part 1 Section 12.3, Part Summary 2.1.7 Part 1 Section 12.3.2...
2.1.6 Part 1 Section 12.3, Part Summary 2.1.7 Part 1 Section 12.3.2, Chartsheet Part 2.1.8 Part 1 Section 12.3.6, Custom XML Mappings Part 2.1.9 Part 1 Section 12.3.7, Dialogsheet Part 2.1.10 Part 1 Section 12.3.19, Single Cell Table Definitions Part 2.1.11 Part 1 Section 12.3...
2.1.6 Part 1 Section 12.3, Part Summary 2.1.7 Part 1 Section 12.3.2, Chartsheet Part 2.1.8 Part 1 Section 12.3.6, Custom XML Mappings Part 2.1.9 Part 1 Section 12.3.7, Dialogsheet Part 2.1.10 Part 1 Section 12.3.19, Single Cell Table Definitions Part 2.1.11 Part 1 Section 12.3...
The NumPy array: a structure for efficient numerical computation. Comput Sci Eng. 2011;13:22–30. Article Google Scholar Krzywinski M, Schein J, Birol I, Connors J, Gascoyne R, Horsman D, et al. Circos: an information aesthetic for comparative genomics. Genome Res. 2009;19:1639–45. ...
Such a cross-contamination rate slightly reduces the contrast in gene expression profiles between different cell subpopulations. However, it is unlikely that a gene would become highly differentially expressed in, and hence become a marker of, a population of cells due to cross-contamination. To ...
$$\begin{array}{ll}{\eta }_{{k}_{{{\rm{geom}}}^{u}=\left\{v\right.\in {{{\mathcal{U}}}\setminus \{u\}| &{{{\rm{cell}}}\,v\,{{{\rm{is}}}\,{{{\rm{within}}}\,{{{\rm{the}}}\,{k}_{{{\rm{geom}}}\\ &\left.{{{\rm{nearest}}}\,{{{\rm{neighbors}...
Since the cells are capsule-shaped, lying roughly horizontally in the embedded samples, we can estimate the spatial chance of detecting a vesicle with diameter x in a random slice going through the round cross section of a cell with diameter y as (Fig. S9): \(\tfrac{x}{y}\) = ...