Cellular organelles called mitochondria contain DNA and can fuse together or split apart. It emerges that excess fusion is averted by stress-activated regulators, preventing the potentially harmful release of mitochondrial DNA. Kate McArthur Michael T. Ryan ...
During division, eukaryotic cells undergo a dramatic, complex and coordinated remodelling of their cytoskeleton and membranes. For cell division to occur, chromosomes must be segregated and new cellular structures, such as the spindle apparatus, must be assembled. Pre-existing organelles, such as the...
Inside the Living Cell: Structure and Function of Internal Cell Parts The cell is the basic, living, structural and functional unit of the body. Cytoplasm 细胞质 The Dynamic, Mobile Factory • Cytosol (细胞溶质)– the gel-like substance enclosed within the cell membrane • Organelles (细胞...
These include aspects of cellular signaling, signal transduction, cell cycle, apoptosis, intracellular trafficking, secretory and endocytic pathways, biogenesis of cell organelles, … View full aims & scope Article publishing options Open Access Article Publishing Charge (APC): USD 3,930 (excluding ...
Aims and scope BBA Molecular Cell Researchfocuses on understanding themechanismsofcellular processesat themolecularlevel. These include aspects of cellular signaling, signal transduction, cell cycle, apoptosis, intracellular trafficking, secretory and endocytic pathways, biogenesis of cell organelles, cytoskeleta...
View PDFAutophagy is an evolutionarily conserved pathway mediating the breakdown of cellular proteins and organelles. Emphasizing its pivotal nature, autophagy dysfunction contributes to many diseases; nevertheless, development of effective autophagy modulating drugs is hampered by fundamental deficiencies in ...
Colon cancer is the third most common cancer and second highest cause of cancer deaths worldwide. The aim of the study was to find new biomarkers for diagnosis, prognosis and therapeutic drug targets for this disease. Four low-grade and four high-grade h
2011; Staněk and Fox 2017). Interestingly, these organelles comprised of RNA and proteins are membrane-less, without any physical boundaries separating them from chromatin and nucleoplasm (Mao et al. 2011; Staněk and Fox 2017). The largest subnuclear structure is the nucleolus, a site of ...
The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments. J. Cell Biol. 111, 2327–2340 (1990). Article PubMed CAS Google Scholar Peters, P. J. et al. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both ...
Characterization of dynamic patterns of alternative splicing and its regulation during spermatogenesis.aBar plot showing the average number of genes with at least two alternative splicing (AS) events at different stages. Error bar represents mean ± SEM.bStacked bar plot indicating the ratio of ...