Cell Adhesion & Migration is a multi-disciplinary, peer reviewed open access journal that focuses on the biological or pathological implications of cell-cell and cell-microenvironment interactions. The main focus of this journal is fundamental science. The journal strives to serve a broad readership ...
Table 1.Prostaglandins in cancer cell adhesion, migration, and invasion summary table. Adhesive factorTissuePGBiological effectRefs Cadherins ↓E-cadherinRIE-S↑PGE2COX-2-mediated PGE2production in rat intestinal epithelial cells (RIE) downregulates E-cadherin[88] ...
Changes in adhesion molecule expression and/or function during cell cycle transit may be critical for engraftment of ex vivo expanded stem/progenitor cells. Here, we studied modulation of adhesion and migration of cell-cycle synchronized LTC-IC. Freshly isolated CB CD34+ cells, which reside in G0...
Cell adhesionis crucial for normal embryonic development and adult maintenance of multi-cellular organisms by regulating cell migration, tissue organization, immune responses, andwound healing[1–4]. Dysregulation of adhesions not only disrupts normal development, but can also contribute to diseases includ...
Interactions of cell adhesion molecules with their environment are central to their regulation and to cell migration and invasion. In the tumor context, the array of integrin receptors expressed causes the cells to differentially respond to external signals, resist the effects of cytotoxic drugs, and...
Intercellular adhesion boots collective cell migration through elevated membrane tension Cell-cell adhesions coordinate collective movement by linking neighboring cells. Here, the authors use artificial photoswitchable adhesions to show that increased membrane tension can drive collective migration. ...
Another microscope—the atomic force microscopy (AFM)-gives unique possibility to visualize structure, topography (Figure 4) and examine mechanical properties of cells (e.g., adhesion force distribution, cells stiffness—Young's modulus as a biomarker of the relative metastatic potential).This method...
[193]. It is responsible for the drug resistance in most of lung cancerous cells [194]. Another tumor marker that mediates critical processes for cancer progression, such as migration, cell adhesion, and tumorigenesis is osteopontin. Its expression rate in tumor cells is 67.8%, while only ...
Initial functional studies suggest that ADGRE5 is relevant for cell adhesion, migration and invasion [53, 59, 68]. To determine ADGRE5 isotype distribution in aggressive lymphoma, we performed Western blot analyses (Fig. 5c) and found that the short isoform (EGF1,2,5) is homogeneously ...
The expression of cell adhesion molecules, immune regulatory molecules and natural killer ligands were thus investigated. A detailed characterization of AT-MSCs under these conditions, with 28 examined markers, is therefore presented. Several changes and alterations within the expression profiles of these...