Interestingly, many fetal interactions were from epicardial-specific collagens, such asCOL11A1andCOL9A3(Extended Data Fig.4), which may play an important part in epicardial-mediated matrix reorganization. Another epicardial collagen,COL3A1, was also found here but was upregulated more broadly in f...
colored by day after reprogramming induction by retroviral overexpression ofFoxa1andHnf4a49; expression of iEP markerApoa1, indicative of reprogramming success; expression of MEF markerCol1a2, indicative of reprogramming failure; or original cluster annotations from Biddy et al.49. Clusters...
Example:'Range','A1:F10' Data Types:char|string UseExcel—Flag to start instance ofMicrosoft®Excelfor Windows false(default) |true Flag to start an instance ofMicrosoft Excelfor Windows when writing spreadsheet data, specified as the comma-separated pair consisting of'UseExcel'and eithertrue,...
(A) Top 50 loadings from PCA1 and PCA2 mostly comprising proteins associated with growth phase and metabolic changes, respectively. Analysis derived from PCA analysis in Figure 4B. (B) Heatmap showing mean expression of proteins, normalized to a −1 to 1 scale, belonging to top 100 GO sl...
Recent study from Satar NA et al. demonstrated that CD166/EpCAM/CD44 triple positive clones mediated therapy resistance and putative CSC characteristics in human non-small cell lung cancer cells [30]. CD49f, (integrin subunit alpha 6, ITGA6), is also identified to be a CSC surface marker,...
In general, we identified 22 cell clusters in liver tissues that could be classified into seven major cell types: B cells (identified by Cd79a, Cd79b, and Ebf1), endothelial cells (identified by Bmp2 and Fabp4), HSC cells (identified by Dcn, Angptl6, Bgn, Colec11, and Col3a1), ...
Endoplasmic reticulum stress in hepatic stellate cells promotes liver fibrosis via PERK-mediated degradation of HNRNPA1 and up-regulation of SMAD2. Gastroenterology 150, 181–193.e8 (2016). CAS PubMed Google Scholar Kim, R. S. et al. The XBP1 arm of the unfolded protein response induces ...
The murine osteoblasts KUSA-A1 (RCB2081, RIKEN cell bank, Saitama, Japan) were cultured in alpha Modified Eagle Minimum Essential Medium with L-Glutamine, ribonucleosides and deoxyribonucleosides medium (Nacalai Tesque, Kyoto, Japan). The murine hepatocytes AML12 (CRL-2254, ATCC) were cultured ...
(GJA1, Figure S4E) [26] as well as the tight junction transmembrane Claudin 1 (CLDN1) and 4 (CLDN4), which are present throughout the cell layers of corneal and conjunctival epithelium [27], suggesting that the cells in this cluster are distinct from the limbal progenitor cells (LPCs)...
(IsFsNio-nβo) fppro3d8βu/ctMioAn.PIKn1a1d[d1i1t]i.on, PIP2 metabolism is disrupted by inflammation and prevents the low membrane concentrations of PIP2 required to in- duce a transition from a TLR4+TIRAP+MyD88 multi-protein-complex, to the TLR4+TRAM+TRIF multi-protein-complex, ...