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deregulated cell death is a common phenomenon of allergic diseases that likely plays an important role in their pathogenesis. Whether the apoptosis is too little or too much depends on the cell type. In this review, we discuss the regulation of the lifespan of the participating ...
In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the pot
were able to generate myogenic cells from mESCs, via the induction of an early mesodermal lineage, using serum-free, chemically-defined, culture media supplemented with the synchronized addition of Bmp4 and lithium chloride (LiCl) (Sakurai et al., 2009). These pioneer studies set the foundation...
Development, 136 (2009), pp. 1363-1374 CrossrefView in ScopusGoogle Scholar Newbern et al., 2008 J. Newbern, J. Zhong, R.S. Wickramasinghe, X. Li, Y. Wu, I. Samuels, N. Cherosky, J.C. Karlo, B. O'Loughlin, J. Wikenheiser, et al. Mouse and human phenotypes indicate a crit...
图. 细胞核生长素信号通路(Cell. 2009 Mar 20;136(6):1005-16) 在拟南芥中,有22个ARF,其都含三个同源结构域:识别生长素响应的N端DBD结构域,中间的MR结构域和C端PB1结构域。PB1结构域介导蛋白质-蛋白质相互作用,其中包括ARF-Aux/IAA和ARF-ARF相互作用。此外,PB1结构域相互作用还促进体外ARF5和ARF7的多...
Human hepatic progenitor cells express hematopoietic cell mar- kers CD45 and CD109. Int. J. Med. Sci. 11, 65–79 (2014). 14. Okabe, M. et al. Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver. Development 136, 1951–1960 (2009). 15. Lee, J....
For Ras, it was measured at about 6–8 molecules per cluster with diameters of 16 nm [61,69]. For Rac1, 20% of the proteins are membrane-bound, forming immobile nanoclusters of ~50–100 molecules with diameters of approximately 200 nm [70]. Interactions with other molecules affect ...