Substrate-level phosphorylation occurs by the transfer of a phosphate group directly from a substrate molecule to ATP. 内容已经隐藏,点击付费后查看 The O2 that we breathe is actually reduced to H2O by the electron-transport chain; it does not form the CO2 that we exhale. 内容已经隐藏,点击付费...
plants and fungi, dyneins are only present in animals and fungi but absent from plants [226]. Dyneins are large, typically minus‐end‐directed multi-subunit motors that exist as cytoplasmic and axonemal forms, of which the latter have dedicated functions in flagellar activity. Each dynein is ...
Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts. Cell 135, 948–959 (2008). CAS PubMed Google Scholar Ligon, L. A. & Holzbaur, E. L. Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly. Traffic 8...
PLK1 and its substrate MISP facilitate intrahepatic cholangiocarcinoma progression by promoting lymphatic invasion and impairing E-cadherin adherens junctions Yi-Ru Pan Joseph Chieh-Yu Lai Chun-Nan Yeh Cancer Gene Therapy (2024) Myosin-independent stiffness sensing by fibroblasts is regulated by the vi...
Rac1 (p21-Rac1, ras-related C3 botulinum toxin substrate 1, ras-like protein TC25, cell migration-inducing gene 5 protein, 192aa); rac2 and rac3 have similar properties but different tissue distributions with rac2 restricted to haematopoietic tuissue; defects in rac2 are the cause of ...
Jiang, W. et al. p190A RHOGAP is a glycogen synthase kinase-3β substrate required for polarized cell migration.J. Biol. Chem.283, 20978–20988 (2008). CASPubMedPubMed CentralGoogle Scholar Cau, J. & Hall, A. Cdc42 controls the polarity of the actin and microtubule cytoskeletons through...
The interplay of cell-cell and cell-substrate adhesion in collective cell migration. Journal of the Royal Society, Interface/the Royal Society. 2014; 11(100):20140684. 58. Hamilton T C, Young R C and Ozols R F. Experimental model systems of ovarian cancer: applications to the design and ...
(-X-V/I/L-X-V/I/L-COOH) have been identified that mediate PDZ-domain/binding protein interactions [129]. The minus one and the minus three position residues (bold) are of particular importance. The last four amino acid residues of the majority of the connexins contain these consensus ...
The N-terminal, cytoplasmic loop, and some membrane-spanning domains of connexins also interact with a variety of proteins, some of which bind the C-ter- minus as well [11,66]. Connexin interactions with cytoskeletal elements Interactions of connexins with cytoskeletal elements are essential in ...
However, dynamic microtubule plus-ends have also been suggested to regulate adherens junction formation52. Hence, microtubule plus- and minus-end binding proteins regulate cell–cell adhesion in interphase cells. Currently, we do not know whether Kif1B binds to core adherens junction proteins ...