AdultPediatric Dosage Forms & Strengths injectable solution 1g/50mL 2g/50mL powder for injection 250mg 500mg 1g 2g 10g 100g Intra-abdominal Infections Complicated, mild-to-moderate, community acquired: 1-2 g/day IV in single daily dose or divided q12hr for 4-7 days, in combination with me...
AdultPediatric Dosage Forms & Strengths injectable solution 1g/50mL 2g/50mL powder for injection 250mg 500mg 1g 2g 10g 100g Intra-abdominal Infections Complicated, mild-to-moderate, community acquired: 1-2 g/day IV in single daily dose or divided q12hr for 4-7 days, in combination with me...
The average values of maximum plasma concentration, elimination half-life, plasma clearance and volume of distribution after a 50 mg/kg IV dose and after a 75 mg/kg IV dose in pediatric patients suffering from bacterial meningitis are shown in Table 3. Ceftriaxone penetrated the inflamed meninges...
Ceftriaxone is highly bound to human serum protein, probably albumin, the extent of binding decreasing from 96% to 83% over the concentration range 0.5 to 300 mg/L. This concentration-dependent serum protein binding is responsible for the non-linear dose-dependent pharmacokinetics of the drug. Th...
Pediatric Infectious Disease 5: 293–297, 1986 PubMed CAS Google Scholar Dattwyler RJ, Halperin JJ, Volkman DJ, Luft BJ. Ceftriaxone is superior to high dose penicillin in the treatment of late lyme borreliosis. Abstract 1276, 17th ICAAC, New York, 1987 De Grandi P, Bauen JF. ...
Pediatric Patients For the treatment of skin and skin structure infections, the recommended total daily dose is 50 to 75 mg/kg given once a day (or in equally divided doses twice a day). The total daily dose should not exceed 2 grams. ...
The average values of maximum plasma concentration, elimination half-life, plasma clearance and volume of distribution after a 50 mg/kg IV dose and after a 75 mg/kg IV dose in pediatric patients suffering from bacterial meningitis are shown in Table 3. Ceftriaxone penetrated the inflamed meninges...
Pediatric Research18,282 (1984)Cite this article 220Accesses Metrics Abstract Thirteen infants (0.4-1.4 yrs) with meningitis were studied. CTX therapy consisted of a 75 mg/kg LD, followed by 50 mg/kg MD every 12 hrs IV over 10 minutes. Simultaneous blood and CSF samples were obtained in ...
The average values of maximum plasma concentration, elimination half-life, plasma clearance and volume of distribution after a 50 mg/kg IV dose and after a 75 mg/kg IV dose in pediatric patients suffering from bacterial meningitis are shown in Table 3. ceftriaxone penetrated the inflamed meninges...
The average values of maximum plasma concentration, elimination half-life, plasma clearance and volume of distribution after a 50 mg/kg IV dose and after a 75 mg/kg IV dose in pediatric patients suffering from bacterial meningitis are shown in Table 3. Ceftriaxone penetrated the inflamed meninges...