1-4 weeks of age - 50 mg/kg per dose every 8 hours IV It is not necessary to differentiate between premature and normal-gestational age infants. Infants and Children (1 month to 12 years): For body weights less than 50 kg, the recommended daily dose is 50 to 180 mg/kg IM or IV ...
Cefotaxime 1 to 2g as a single preoperative dose or as a short course of 3 to 4 doses at 8-hourly intervals peri- and/or postoperatively has proven highly effective in the prevention of infection following a wide range of surgical procedures (urological, obstetrical and gynaecological, gastroin...
Following a single intramuscular dose of cefotaxime (10 mg/kg), the absorption half-life and elimination half-life were 0.13±0.03 h and 2.97±0.72 h, respectively. The apparent volume of distribution and total body clearance were 3.28±0.72 L/kg and 0.78±0.08 L/kg per h, respectively. ...
Treatment of meningitis patients can be increased to 6 75mg/kg per hour, all intravenous administration. Patients with severe renal failure should be appropriately cut down when using this product. When the serum creatinine value exceeds 424 mol/L (4.8mg) or the creatinine clearance rate is ...
Healthy neonatal foals were treated with cefotaxime by bolus (40mg/kg IV q6h for 12 doses; n=10) or by infusion (loading dose of 40mg/kg IV followed by continuous infusion of a total daily dose of 160mg/kg per 24h for 3days; n=5). Population pharmacokinetics was determined, and ...
Such carriers are well known in the art, and the specific carriers employed may be varied depending upon factors such as size of the subject being treated, treatment dose, and the like. When administered in combination with other therapeutic agents, both the lysozyme and the other agent(s) ...
Figure 3.Concentration of CFT versus time and elimination of CFT (insert) in hepatopancreas (A) and plasma (B) of white leg shrimp (n= 6) after administration of a single oral dose (25 mg/kg shrimp); the data are expressed as mean ± standard error; MIC, minimal inhibitory concentrat...