Cefepime was more active against Enterobacteriaceae than ceftazidime (93% vs. 72%, p < 0.001). This superiority was most evident against nosocomial strains of K. pneumoniae, against which cefepime was > three times more active than ceftazidime. The high level of resistance seen in nosocomial ...
Vaborbactam possesses a more limited inhibitory profile that does not include OXA-48 carbapenemases (44); therefore, incomplete coverage of OXA-48-producing CRE by meropenem-vaborbactam is the reflection of the unprotected meropenem activity. Ceftazidime-avibactam and cefepime-taniborbactam showed ...