Its activity against common pathogens is comparable to that of group 4 cephalosporins, but it is somewhat more active against Ps. aeruginosa. Like cefpirome it has low affinity for the molecular class C cephalosporinases of many Gram-negative rods and is consequently active against most strains of...
Methods: The minimal inhibitory concentrations of 1521 Gram-positive cocci and 3170 Gram-negative rods were determined by the Etest procedure. Results: The susceptibilities were as follows. Gram-positive bacteria: cefepime, 92.7%; ceftazidime, 60.5%; ceftriaxone, 87.8%; imipenem, 92.6%; amikacin, ...
Its activity against common pathogens is comparable to that of group 4 cephalosporins, but it is somewhat more active against Ps. aeruginosa. Like cefpirome it has low affinity for the molecular class C cephalosporinases of many Gram-negative rods and is consequently active against most strains of...
Calculated parenteral initial treatment of bacterial infections: infections with multi-resistant gram-negative rods– ESBL producers, carbapenemase-producing Enterobacteriaceae, carbapenem-resistant Acinetobacter baumannii. GMS Infect Dis. 2020;8:1–22. Kaur R, Gautam V, Singhal L, et al. Antimicrobial ...
The cefepime spectrum was broader than that of the other broad-spectrum cephalosporins against both Gram-negative rods and Gram-positive cocci. Cefepime was particularly more active against Enterobacter sp. (MIC90, 2 micrograms/ml), Serratia sp. (MIC90, 2 micrograms/ml) and oxacillin-susceptible ...