Compares the safety profile of cefepime, a new extended-spectrum, fourth-generation cephalosporin used to treat mild-to-severe bacterial infections, with that of ceftazidime, the third-generation cephalosporin. Discussion of data from North American and European clinical trials of cefepime; Comparison ...
The purpose of this study was to compare the safety profile of cefepime, a new extended-spectrum, fourth-generation cephalosporin used to treat mild-to-severe bacterial infections, with that of ceftazidime. A total of 2,032 patients enrolled in North American and European cefepime trials were ana...
cefepime Medical Wikipedia Related to cefepime:Cefixime cef·e·pime (sĕf′ə-pēm′) n. A broad-spectrum cephalosporin antibiotic, C19H24N6O5S2, used in its hydrochloride form to treat a variety of infections, including skin and urinary tract infections and certain types of pneumonia. ...
Synopsis Cefepime is a 'fourth' generation Cephalosporin that has a broader spectrum of antibacterial activity than the third generation Cephalosporins and is more active in vitro against Gram-positive aerobic bacteria. The fact that cefepime is stable to hydrolysis by many of the common plasmid and...
Cefepime is a broad-spectrum fourth-generation cephalosporin with activity against both gram-positive and gram-negative bacteria, including Pseudomonas aeruginosa. Cefepime is most commonly used for urinary tract infections, soft tissue infections, and febrile neutropenia. Cefepime does not work against inf...
Definition (NCI) A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling ...
Cefepime is a parenteral fourth-generation cephalosporin antibiotic with an extended spectrum of antimicrobial activity, active against many grampositive and gram-negative bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, and Staphylococcus aureus. It is excreted primarily unchanged in the urine, ...
Actions and SpectrumBased on spectrum of activity, classified as a fourth generation cephalosporin. Expanded spectrum of activity compared with first and second generation cephalosporins and more active than third generation cephalosporins against Enterobacteriaceae that produce inducible β-lactamases. More ...
Cefepime/Enmetazobactam: First Approval Cefepime/enmetazobactam (EXBLIFEP), an intravenous (IV) antibacterial fixed-dose combination of a 4th generation cephalosporin and an extended-spectrum 尾-... SJ Keam - 《Drugs》 被引量: 0发表: 2024年 ...
Cefepime is the fourth-generation cephalosporin and has an extended spectrum of activity against GNB. It lacks activity against ESBLs but it is stable against AmpC, while tazobactam is active against ESBLs. As a result, it is anticipated that Enterobacterales will become more susceptible when cef...