(2007). Five members of the CEBP transcription factor family are targeted by recurrent IGH- translocations in B-cell precursor acute lymphoblastic leukemia (BC-ALL). Blood 109: 3451-3461.Akasaka T, Balasas T, Russell LJ, Sugimoto KJ, Majid A, Walewska R, et al. Five members o...
C A Cantwell and P F Johnson linked leucine zipper dimers in vitro. A family of C/EBP-related proteins capable of forming covalently References http://genesdev.cshlp/content/5/9/1553.full.html#ref-list-1 This article cites 58 articles, 35 of which can be accessed free at: Service Email...
One proposed mechanism was sequestration of its CEBP family dimerization partners [21]. DDIT3 expression in liposarcoma development The Avtex ComputerTalk partnership will bring Lync unified communications and CEBPs into contact centers and to extend the power of contact centre applications to the rest...
We conclude that STAT3 is a driver of the metastatic process in melanoma and able to antagonize MITF via direct induction of CEBP family member transcription. This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 50 print issues ...
whichtheyactasactivatororinhibitorinregulatingtranscription.All thesevariousfunctionsofC/EBPsarerelatedtotheirspecialstructuresthatcharacterizethe membersofbZIPfamily.Withthemselvesorotherisoforms,C/EBPscanformhomodimers orheterodimersthatcontaindifferentregulationalinformations.Furthermore,theycan interferewithawidevariety...
Supplementary Figure 14 Bioinformatics analyses of Smarcd1, Smarcd2, Smarcd3 and CEBP family proteins. (a) Bioinformatics studies revealed that the SWIB domain of SMARCD2 (of unknown function) is closely related to hydrophobic regions of MDM2 that allow interaction with the p53 α-helix (from Benn...
Forms a complex with THOC5 (By similarity). Interacts with ZNF638; this interaction increases transcriptional activation (By similarity).Subcellular Location : Nucleus.Tissue Specificity : Liver and lung.Similarity : Belongs to the bZIP family. C/EBP subfamily.Contains 1 bZIP domain. ...
CEBP alpha (CCAAT/Enhancer-Binding Protein; also C/EBP) is a 42-43 kDa member of the C/EBP subfamily, bZIP family of proteins. It is expressed in multiple cell types, particularly those that are fully differentiated, and includes hepatocytes, skeletal muscle cells, adipocytes, intestinal epithe...
(CCAAT enhancer binding protei)family,whose C-terminal region contai the highly coerved DNA-binding domain and dimerization domain. C/EBP β plays important roles in numerous cellular respoes by regulating the tracripition of genes from target cells,including the cell proliferation and diferenti...
This suggests that the cooperation of PPAR with C/EBP family members is necessary for optimal differentiation, although the precise mechanism of this cooperation remains unclear. Based on in vitro studies and target genes identified in 4 Corresponding author. E-MAIL lazar@mail.med.upenn.edu; FAX...