However, in order for the HC-CDR3 variant to be combined with only 10 of these combinations, the duplication level of the HC-CDR3 region must also be around 10. Even for short HC-CDR3 loops this would imply to increase the fraction of that loop length in the library by a factor of...
VDP used de-duplication which means that we copy on on block level. Saving space : dedupe store • Put the same egg in the same bucket VDP sort and keep similar block Deduplication VDP - Application Backup • Flexible VDP storage management ...
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