cdp-choline pathway CDP-胆碱途径
and Brehier, A,: The T'DPcholine pathway: cholinephosphate cytidylyltransferase. In: Lung De~'doprn~nBii:ologicul and Clit~rcoPl erspc,c- i i ~ ~ e s1/.01, I . Biocirernicirl~ond P/~!~.sro/ogyF.arrell PM, ed. pp. 317-335 (Academic Press, New York. 1982)....
The CDP–choline pathway of phosphatidylcholine (PtdCho) biosynthesis was first described more than 50 years ago. Investigation of the CDP–choline pathway in yeast provides a basis for understanding the CDP–choline pathway in mammals. PtdCho is considered as an intermediate in a cycle of synthesi...
1::URA3) also displayed an identical mode of regulation in response to inositol as did cells containing an intact EPT1 gene (wild type) indicating there is no requirement for an alternate functional CDP-amino-alcohol pathway for inositol to regulate PC synthesis via the CDP-choline pathway. ...
Cytidine 5'-diphosphocholine, CDP-choline or citicoline, is an essential intermediate in the biosynthetic pathway of the structural phospholipids of cell membranes, especially in that of phosphatidylcholine. Upon oral or parenteral administration, CDP-choline releases its two principle components, cytidine...
Cytidine-5′-diphosphocholine (CDP-choline or Citicoline) is composed of cytidine and choline linked by a diphosphate bridge and is an essential intermediate in the synthesis of phosphatidylcholine (PC), a major brain phospholipid, via Kennedy pathway. Exogenous CDP-choline is hydrolyzed and...
This phenotype is reversed in cells that also overproduce the yeast cholinephosphatecytidylyltransferase (CCTase). The SEC14p is shown to act as a negative regulator of the CDP-choline pathway through the ligand-modulated SEC14p dependent inhibition of CCTase. PC bound SEC14p is identified as ...
The first is the cytidine pathway ori... S Spanner,GB Ansell - Springer US 被引量: 2发表: 1978年 CDP-choline modulates matrix metalloproteinases in rat sciatic injury Background: CDP-choline (cytidine-5'-diphosphocholine) improves functional recovery, promotes nerve regeneration, and decreases ...
Top of pageThe interferon regulatory factor 1 (IRF-1) is a positive transcriptional regulatory protein which acts in the interferon signal transduction pathway to activate the transcription of the type I interferon genes by binding to the PRDI response element. The aim of this study was to explo...
Introduction The cholinergic anti-inflammatory pathway (CAP) is a physiological mechanism that inhibits cytokine production and minimizes tissue injury during inflammation. CAP-mediated anti-inflammatory signals in vagal efferent nerve fibers result in the release of acetylcholine, which interacts with innate...