Women with CDH1 mutations are at increased risk for breast cancer and should be followed using high-risk guidelines as outlined in the NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian.【NCCN 29/122】 选择不接受预防性胃切除术的CDH 1突变携带者,应每6-12个月接受内窥...
breast cancer risk due to cdh1 p/lp variants in a north american cohort. cdh1相关癌症风险的最初估计来自不到12个高风险家族,其中包括新西兰奥特亚土著毛利人.1,6随后对在商业实验室接受遗传性癌症适应症基因测试的个体的数据进行分析,估计终身癌症风险为癌症25%至...
breast cancer (multiple); cervix uteri carcinoma in situ; gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Biomarker of several diseases, including endocrine gland cancer (multiple); invasive lobular carcinoma; oral squamous cell carcinoma; prostate cancer; and pulmonar...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook ecad (redirected fromCDH1) Medical Encyclopedia Related to CDH1:Cadherin 1 ecad (ˈiːkæd) n (Biology) an organism whose form has been affected by its environment ...
An in vivo study of Cdh1/APC in breast cancer formation. Int J Cancer 2009; 125:826-36.Fujita T,Liu W,Doihara H,et al.An in vivo study of Cdh1/APC in breast cancerformation. International Journal of Cancer . 2009An in vivo study of Cdh1/APC in breast cancerformation. Fujita T,Liu...
【7】The frequency of PVs in breast cancer predisposition genes among women with invasive lobular carcinoma was 6.5% in the clinical cohort and 5.2% in the population-based cohort. 【8】In case-control analysis,CD...
Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. JAMA Oncol. 2015;1:23-32. [PubMed] [DOI] 6. Minikes AM, Song Y, Feng Y, Yoon C, Yoon SS, Jiang X. E-cadherin is a biomarker for ferroptosis sensitivity in diffuse gastric cancer. Oncogene. 2023;42:848-857. ...
细胞生物学: 培养基和添加剂 细胞培养血清
a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. Th...
Mutations in this gene are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian ...