Subsequently PAP rose and repeat doses of TZL and CPZ administered into the MPA caused little response, 14 hours later the infant died. PH complicating CDH probably occurs frequently. Establish ment of pulmonary normotension may be necessary for survival....
pulmonary hypertension are sildenafil and prostacyclin, which have a role in select patients. ECMO should be considered with suprasystemic pulmonary hypertension and a preductal saturation of less than 85% using a gentle ventilation protocol. Anesthesia The airway should be controlled with oro...
The high mortality for congenital diaphragmatic hernia (CDH) has been attributed to a combination of pulmonary hypoplasia and pulmonary hypertension. We hypothesize that a surfactant deficiency may in part be contributing to the pathophysiology of CDH. This study documents the functional, quantitative, ...
PERSISTENCE OF PULMONARY HYPERTENSION (PHT) IN AN ECMO/CONGENITAL DIAPHRAGMATIC HERNIA (CDH) POPULATION. ??? 15341996 Abstracts The American Pediatric Society and The Society for Pediatric Researchdoi:10.1203/00006450-199604001-01557J C Bernbaum
PurposeBoth the mortality and morbidity associated with congenital diaphragmatic hernia (CDH) are mainly caused by pulmonary hypoplasia and persistent pulmonary hypertension. A previous study revealed that insulin-like growth factors (IGFs) play important roles in fetal lung development. The aim of this...
Following operation none of the eight infants developed PFC and all survived. We conclude that prolonged preoperative ventilation until pulmonary hypertension has resolved prevents PFC and improves the prognosis of CHD. Article PDF Author information Authors and Affiliations University Hospital, Trondheim, ...
Adiponectin has been implicated in the development of chronic obstructive pulmonary disease (COPD). TheCDH13gene encodes T-cadherin that is an adiponectin receptor, and genetic variants ofCDH13determine blood adiponectin levels. The aim of this study was to investigate the effects ofCDH13variants on...
PULMONARY-HYPERTENSION (PH) AND CONGENITAL DIAPHRAGMATIC HERNIA (CDH)doi:10.1203/00006450-197404000-00771POMERANC.JJRICHARDS.CJCOLLINS, DTRAVIS, KWTURNER, SWPEDIATRIC RESEARCH
Pulmonary hypertensionProstacyclinsClinical outcomesCONGENITAL DIAPHRAGMATIC-HERNIAARTERIAL-HYPERTENSIONTREPROSTINILSAFETYWhile the proportion of patients receiving a prostacyclin for management of CDH-PHTN has remained relatively stable over the last 13years, there is significant variation in timing of initiation ...
diaphragm, frequently associated with significant pulmonary complications and mortality, due to protrusion of abdominal viscera into the chest cavity.We aim to describe the case of a 38-week-old female child with prenatal diagnosis of left-sided CDHwith hypoplastic left lung...