Specificity / Sensitivity Cdc2 (E1Z6R) Rabbit mAb recognizes endogenous levels of total cdc2 protein. Species Reactivity: Human, Mouse, Rat, Hamster, MonkeySource / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding...
carinii Cdc2 polypeptide. Given this amino acid sequence, antibodies with specificity for an epitope defined by this amino acid sequence may be prepared by immunizing a suitable animal such as a rabbit. Polyclonal and monoclonal antibody production and purification techniques are standard in the art....
1991 . A monoclonal antibody against the PSTAIR sequence of p34 cdc2 , catalytic subunit of maturation-promoting factor and key regulator of the cell cycle. Develop. Growth Differ. 33 , 617 624 .Yamashita M , Yoshikuni M , Hirai T , Fukada S , Nagahama Y . 1991 . A monoclonal antibody...
SpecificityThe antibody detects endogenous level of CDK1/CDC2 only when phosphorylated at threonine 14. Immunogen TypePeptide-KLH Immunogen DescriptionPeptide sequence around phospho rylation site of threonine14(E-G-T(p)-Y-G) derived from Human CDK1/CDC2 . ...
(TNBC). The compound CC-671, an inhibitor of both CLK2 and the dual-specificity protein kinase TTK, blocked the growth of two cell lines and a patient-derived TNBC xenograft29. CLK2 also affects cell survival following ionizing radiation. The overexpression of CLK2 inhibits cell death induced...
(b), with the rabbit antiserum to Cdc2 (e and g) together with the antibody to TAG-1 (f) or a mouse monoclonal antibody to the neuron-specific β tubulin (TuJ1) (h), or with a mouse monoclonal antibody to Cyclin B1 (i) together with a rabbit antibody to the neuron-specific ...
50 μg/ml aprotinin, 50 μm leupeptin, and protein extracts were immunoprecipitated with a rabbit polyclonal antibody raised against the COOH terminus (amino acids 479–502, NSGPYKKQAFPMISKRPEHLRMNL) of p70s6k(anti-p70s6kCT antibody) or a mouse monoclonal anti-HA monoclonal antibody (12CA5)...
A monoclonal antibody derived from the melanoma gene in the Xiphophorus melanoma model American Journal of Pathology 143(3): 656-662 Wilson-Robles, H.M.; Daly, M.; Pfent, C.; Sheppard, S. 2015: Identification and evaluation of putative tumour-initiating cells in canine malignant melanoma ...