带你了解系统性红斑狼疮 近期我科收治了两例年龄分别为13岁及22岁的女性患者,起病表现分别为眼睑水肿及血白细胞减少,而在入院完善相关检查后,均诊断为系统性红斑狼疮。系统性红斑狼疮(Systemic Lupus Erythematosus,简称SLE)因其复杂的发病机制、多样的临床表现以及漫长的治疗过程,成...
Additionally, the document revises recommendations on contraceptive use for patients with a variety of medical conditions or characteristics, including individuals who are breastfeeding, postpartum, and postabortion. Other factors considered include obesity, surgery, history of deep venous thrombosis or...
系统性红斑狼疮(Systemic Lupus Erythematosus,SLE)是一种自身免疫性疾病,大多发病缓慢,临床表现多样、易侵及许多系统和脏器的自身免疫性疾病。SLE可累及皮肤、浆膜、关节、肾脏、血液、呼吸、消化以及神经系统等,并以自身免疫为特征。患者体内存在多种自身...
3. Distinct pathways found to be overrepresented in Cdc42 transfected cells were underrepresented in cells treated with Cdc42 specific siRNA (e.g. oxidative phosphorylation and calcium signalling) and vice versa (systemic lupus erythematosus), indicating a regulatory role for this GTPase on these ...
系统性红斑狼疮;B淋巴细胞活化因子/增殖诱导配体; 临床试验_正文_系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种累及多系统、多器官、与多种自身抗体相关的自身免疫性疾病,好发于20～40 岁的育龄期女性。临床表现复杂多样,常常累及肾脏、脑等重要脏器,导致严重器官功能障碍。SLE确切的发病机制尚未阐明,遗传...
In a multi-centre prospective study of systemic lupus erythematosus and pregnancy in France, 117 cases were identified from 1987 to 1992. We report significant morbidity and mortality for mother and fetus from an analysis of 103 cases. Pregnancy outcome was as follows: 28 full-term births, 48 ...
Mycophenolate mofetil for the treatment of systemic lupus erythematosus: an open pilot trial OBJECTIVE: To investigate the effectiveness and safety of mycophenolate mofetil in patients with systemic lupus erythematosus who were inadequately control... M Gaubitz,A Schorat,H Schotte,... - 《Lupus》 ...
抗核糖体P蛋白抗体、抗Sm抗体和抗双链DNA抗体联合检测在系统性红斑狼疮诊断中的价值
1 正确认识系统性红斑狼疮 SystemicLupusErythematosus,SLE（Lupus=Wolf）是一种自身免疫性疾病（免疫紊乱所造成)不是传染性疾病不是遗传性疾病（具有遗传倾向性）是一种慢性、炎症性疾病 多种自身抗体、多脏器受累，病程迁延反复不是恶性疾病 2021/8/31 2 流行病学 中国有多少狼疮患者呢？发病率4-250/10万人，...
系统性红斑狼疮 (systemic lupus erythematosus, SLE) 是一个全身性疾病。它常带来肾脏问题,即为狼疮肾炎 (lupus nephritis, LN)。LN 带来更高的死亡率、残疾率。如何控制 LN 成为改善中-重症狼疮患者预后的主要挑战。 LN 的流行病学 诊断为 SLE 的患者中最终约 50% 的...