研究背景:弥漫大B细胞淋巴瘤(Diffuse large B cell lymphoma,DLBCL)是最常见的血液系统恶性肿瘤,全球每年发病超过100000例.尽管近年来DLBCL的诊断和治疗有了较大的进步,但仍有高达30%的患者死于该疾病.目前DLBCL的发生机制尚不完全清楚,因此有必要寻找在肿瘤发生,发展中起关键作用的核心基因和信号通路,进一步揭示DLBCL...
Allelic Diversity and Affinity Variants of MICA are Imbalanced in Spanish Patients with Behcet's Disease. The aetiology of Behcet's disease (BD) is still unknown, but genetic and environmental factors are involved. HLA-B*51 is considered a susceptibility marker... SI Munoz,A Cambra,L Pallares...
关键词: humoral immune response immune protection immunoglobulins B lymphocytes isotypes 被引量: 83 摘要: The present invention relates to antibodies which are capable of being conjugated at specific sites, to processes for the site-directed conjugation of such antibodies, to antibodies that have ...