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Moreover, in mice, T cell immunoglobulin and mucin domain containing 4 (TIMD4, better known as TIM4), the phosphatidyl serine receptor, facilitates antigen uptake by tissue-resident lung cDC1s, thus driving tumor immunosurveillance [52]. In human lung adenocarcinoma, TIM4 expression correlated ...
Proteomic analyses identified a phosphorylation site for S171 (ref. 41), which is in the centre of the flexible loop preceding helix a9 (Supplementary Fig. 4) and not resolved in the crystal struc- ture. We introduced two aspartates at the site of S171 as a mimic of a negatively ...
Finally, the actin factor describes the regulation of cell morphodynamics by GTPase signaling pathways that induce actin polymerization driving cell edge movement. We assume that, in the absence of GTPase activity, the regulation is neutral, i.e., that this factor does not contribute to the relati...
Essentially, this refers to the driving of powder down a pathway of lowering power-to-powder contact, to instead increase powder-to-wall contact. When there is resistance to this gradient of increasing powder-to-wall interactions, it suggests there is a lack of flowability, which commonly ...
🔷如需引用“锦鲤英语”文章,请注明出处:“本文源自锦鲤英语” 。 2022年连云港市初中学业水平考试英语试题一、单项选择(共15小题;每小题1分,满分15分)从每题所给的A、B、C、D四个选项中选出最佳选项。1. Me and My Winter Games isinteresting film. I...
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Actin filaments are thought to contribute to the maintenance of the flattened shape of Golgi cisternae4, 30, and can facilitate membrane deformations driving processes as various as vesicle formation, scission and fusion. However, specific staining of actin filaments at the Golgi using phalloidin appea...
Thus, a plausible explanation for the synthetic lethality of rdi1Δ bem2Δ mutants is that loss of the GAP elevates overall GTP-Cdc42 levels, driving a “leakage” flux of GTP-Cdc42 through the cytoplasm to outlying membranes and dissipating polarity (Figure 7K). This flux can be ...