CD95 expression and CD95-mediated apoptosis of T cells in multiple sclerosis. No differences from normal individuals and no relation to HLA- DR2. J Neuroimmunol 1998;81:168 -172.ZIPP F, FABER E, SOMMER N et al. CD95 expression and CD95-mediated apoptosis of T cells in multiple ...
Ontogenic changes in CD95 expression on human leukocytes prevalence of T-cells expressing 热度: 癌症细胞凋亡与细胞死亡 热度: 细胞凋亡与细胞死亡机制 热度: 相关推荐 文章编号:1004-616X(2001)01-0055-03・综述・ 死亡分子Fas/CD95与细胞凋亡 ① 赵艳 综述,吴坤 审校 (哈尔滨医科大学公共卫生学院...
It was proposed that the expression of CD95L on 'antigen-presenting cells' (APC) would be responsible for antigen-specific deletion of primed peripheral T cells, eventually leading to T cell tolerance or immunosuppression [60–62]. Follow-up studies, however, provided evidence for alternate activ...
expression regulation of gene expression positive regulation of cell death B cell mediated immunity dendrite regeneration positive regulation of protein homooligomerization tumor necrosis factor-mediated signaling pathway regulation of cell proliferation regulation of apoptotic process T cell homeostasis positive ...
CD95 (APO-1, Fas) is a member of the tumor necrosis factor (TNF) receptor superfamily expressed in various tissues; however, expression of its ligand CD95L, a type II transmembrane protein of the TNF family, is restricted to a few cell types, such as T cells, macrophages, and cells ...
. Interaction of CD95 on mature lymphocytes with its ligand (FasL) induces apoptosis and is thought to be important in peripheral tolerance. 15A7 reacts with mouse CD95 in BALB/c strain and a bit more weakly in C57Bl/6 strain. 15A7 does not induce apoptosis of Fas-expressing cells....
Description: The DX2 monoclonal antibody reacts with human CD95 (Fas, Apo-1), a 40-50 kDa member of the TNFR superfamily. CD95 is expressed by a broad range of hematopoietic and non-hematopoietic cells including monocytes, neutrophils, lymphocytes and fibroblasts. Interaction of CD95 on mature...
This change does not affect any figure or result reported in the manuscript, but does affect the conclusions: the suppressive effect of LUCA-15 on CD95-mediated apoptosis was due to suppression of LUCA-15 gene expression rather than overexpression of LUCA-15. A new manuscript, describing the ...
tions.Methods:Four—colorflowcytometrywasusedtodeterminetheexpressionofCD95,CD45RO,CD45RAon CD4 TlymphocyteinperipheralbloodfromHIV一1infectionsubjectsandserumFaslevelswerequantifiedbyen— zyme—linkedimmunosorbentassay(ELISA).Results:Comparedwithhealthycontrols,serumFaslevelsweresig— ...
It was proposed that the expression of CD95L on 'antigen-presenting cells' (APC) would be responsible for antigen-specific deletion of primed peripheral T cells, eventually leading to T cell tolerance or immunosuppression [60–62]. Follow-up studies, however, provided evidence for alternate activ...