CTLA4-CD80/CD86 interactions on primary mouse CD4+ T cells integrate signal-strength information to modulate activation with Concanavalin A. J. Leukoc. Biol. 2005 Mar 23; [Epub ahead of print] Murphy G, Bretz U, Baggiolini M, Reynolds JJ. The latent collagenase and gelatinase of human ...
B7(CD80 CD86) 和CD 28结合产生共刺激信号激发T细胞分化 增殖分泌白血球介素2--IL-2等细胞因子放大免疫系统的反应 细胞毒...
Here IL-10 but not transforming growth factor-beta plays a functional role. In summary, CTLA4-CD80/CD86 interactions on T cells integrate signal strength, based on the dose of Con A, to enhance or inhibit primary mouse CD4(+) T cell cycling and survival. 展开 ...
Background Xenotransplantation is a promising approach to circumventing the current organ shortage. However, T-cell-dependent anti-xenoresponses are a major challenge to successful xenografts. Given the advantages of the use of CTLA4-Ig in the survival o
百度试题 题目下列哪种组合是B细胞活化的第二信号: A.CD86-CD28B.B7-CTLA4 C.CD80-CD28D.B7-CD28E.CD40L-CD40相关知识点: 试题来源: 解析 E 反馈 收藏
Mukherjee S, Ahmed A, Malu S, Nandi D (2006) Modulation of cell cycle progression by CTLA4-CD80/CD86 interactions on CD4 + T cells depends on strength of the CD3 signal: critical role for IL-2. J Leukoc Biol 80:66Mukherjee, S., A. Ahmed, S. Malu, and D. Nandi. 2006. ...
A peptide EL161 derived from CD80-binding domain (MYPPPY motifs) in the complementarity determining region (CDR) 3 of CTLA4 was found to inhibit the interaction of CTLA4 with CD80 significantly. Afterward, the peptide EL16 as well as the CDR1 of CTLA4 which is also critical for its ...
Modulation of cell cycle progression by CTLA4-CD80/CD86 interactions on CD4+ T cells depends on strength of the CD3 signal: critical role for IL-2. J. Leukoc. Biol. 80: 66-74.Mukherjee S, Ahmed A, Malu S and Nandi D. Modulation of cell cycle progression by...
A peptide EL161 derived from CD80-binding domain (MYPPPY motifs) in the complementarity determining region (CDR) 3 of CTLA4 was found to inhibit the interaction of CTLA4 with CD80 significantly. Afterward, the peptide EL16 as well as the CDR1 of CTLA4 which is also critical for its ...
CD80 (B7|[ndash]|1); cytotoxic T lymphocyte|[ndash]|associated protein 4 (CTLA4; CTLA-4; CD152)A study in cell culture suggests that antagonizing B7–1 on myeloid dendritic cells (DCs) could help treat inflammation associated with emphysema. Further details on the research, next steps and ...