Two-stage CD8+CAR T-cell differentiation in patients with large B-cell lymphoma Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease group with CAR T cells offering therapeutic success in otherwise
CD8+ T-cell lymphomaInterferonUlcerated skin nodulePrimary cutaneous aggressive CD8+ T-cell lymphoma is an extremely rare entity with distinct clinicopathological features. We report a case of a 28-year-old man that clinically presented with an ulcerated nodule on his trunk and extremities. ...
Adachi, T. et al. Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nat. Med. 21, 1272–1279 (2015). Article CAS PubMed PubMed Central Google Scholar Mackay, L. K. et al. T-box transcription factors combine with the cytokines TGF-β...
Primary extranodal CD8 positive epitheliotropic T-cell lymphoma arising in a leiomyoma of the uterus[J] . H Merz,K Lange,B.U Koch,O Bauer,P Gaulard,A.C Feller.BJOG: An International Journal of Obstetrics and Gynaecology . 2003 (5)
Primary cutaneous aggressive CD8+ T-cell lymphoma is an extremely rare entity with distinct clinicopathological features. We report a case of a 28-year-old man that clinically presented with an ulcerated nodule on his trunk and extremities. Histopathologic sections showed an ulcerated epidermis with ...
CD8‐positivecutaneous T‐cell lymphomalymphoproliferativeprimary cutaneous acralPrimary cutaneous acral CD8 (+) Tヽell lymphoma is a rare, distinct type of cutaneous Tヽell lymphoma. Despite its worrisome histological appearance it has a benign clinical course. It is therefore important to recognise ...
The current classification of primary cutaneous T-cell lymphoma (CTCL) of the World Health Organization (WHO) includes primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma as a provisional entity awaiting cumulative data. Recent reports identify CD3/CD8-positive clonal T-...
CD8-positive T cells Hodgkin lymphoma T-cell lymphoma T-helper 17 cells T-helper 1 cells T cells Introduction Classic Hodgkin lymphoma (CHL) is histologically composed of Hodgkin Reed-Sternberg (HRS) cells and the tumor microenvironment (TME) consisting of T-cells and macrophages [1, 2...
(C) The percentage of CD8 T cells positive for one or more of the cytokines IFNγ, TNF-α, and IL-2. (D) The distribution of single-, double-, and triple-positive cells within all cytokine-producing CD8 T cells. (E) Multi-functional CD8 T cells, defined as producing more than one...
Single-cell RNA analysis reveals cell-intrinsic functions of CAR-T cells correlating with response in a phase II study of lymphoma patients Clinical Cancer Research; IF: 11.500; DOI: 10.1158/1078-0432.CCR-23-0178 内容概要:通过scRNA-seq分析CAR-T细胞治疗中影响治疗效果的因素,发现具有高多功能性、...