Increase of CCR7-CD45RA+ CD8 T cells (T(EMRA)) in chronic graft-versus-host disease. Leukemia. 2006;20:545–7.D'Asaro M, Dieli F, Caccamo N, Musso M, Porretto F, Salerno A. Increase of CCR72 CD45RA1 CD8 T cells (TEMRA) in chronic graft-versus-host disease. Leukemia. 2006;20...
nnenberg,W Gooding,TL Whiteside.Effector CD8+ CD45RO-CD27-T cells have signalling defects in patients with squamous cell carcinoma of the head and neck... I Kuss,AD Donnenberg,W Gooding,... 被引量: 0发表: 0年 Effector CD8|[plus]|CD45RO|[minus]|CD27|[minus]|T cells have signalling...
3D), suggesting a possible origin from newer CD28−CD45RA−, which lost CD28 as a result of Ag-mediated stimulation. Of note, in the tumor site also CD137 and ICOS failed to provide functional advantage to CD28- T cells, nevertheless still sustained by CD11ahigh, although expressed ...
This observation is in agreement with an earlier study that found few endometrial CD45RA positive CD8-T cells–the majority were CD45RA−/CCR7− indicative of the effector memory subset2. We hypothesised that this predominant CD8-T memory cell population would be Trm and therefore analysed ...
(G) Distribution among subsets defined by expression levels of PD-1 and CD127. (H) Expression of the transcription factors TCF1 and BCL2. Dotted lines indicates fluorescence-minus-1 controls. MFI, median fluorescence intensity; ND, not done; P, patient; TCM, central memory; TEM, effector ...
Moreover, relatively high doses of some monoclonal antibodies [anti-B220 (CD45RA) and anti-CD23 (IgE Fc epsilon II receptor)] were necessary to completely eliminate all contact sensitivity-initiating cells that permitted expression of late contact sensitivity-effector T-cell activity. In contra...
8 They demonstrated that PRAME-specific CD8+ T cells in healthy donors reside in the CD45RA+ T-cell compartment; however a similar analysis was not performed in patients with CML. We were unable to perform phenotypic analysis of PRA300-specific CD8+ T cells in healthy donors due to ...
Cells were expanded for 10 days, selected for Thy1.1 using a CD90.1 Positive Selection Kit (StemCell Technologies), and stained for Thy1.1 and IL2RA. Transduced cells in the lower and upper 10% tails of IL2RA expression were sorted for subsequent gRNA library construction and sequencing. ...
expression is proportional to CD25 expression in circulating CD4+ CD45RA+ CD25+ and CD4+ CD45RA-CD25++ cell subsets63,64,65. Fifth, we were not able to compare the concentrations of plasma markers of inflammation nor individual metabolites between the cohorts, since the measurements were ...
The results are expressed as the mean cpm plus or minus SD for tritiated thymidine incorporation by 50 × 103 cells during the last 18 hours of a 3-day culture. Download: Download full-size image Fig. 4. Immobilized anti-CD3 mAbs increased cytokine-induced proliferative responses of the tumor...