Thus, acutetreatment with low-dose methamphetamine after severe TBI caused a transientbilateral increase of Iba1+cellswithin the granule layer of the dentate gyrus but did not alter the overalltemporal and regional pattern of Iba1 and CD68 staining within the cortex,periventricular white matter, ...
是主动免疫防御的主要形式。现在一般采用CD68、F4/80、iba1、TMEM119启动子作为小胶质细胞特异性启动子。
Anti CD163+, Iba1+, and CD68+ Cells in the Adult Human Inner Ear: Normal Distribution of an Unappreciated Class of Macrophages/Microglia and Implications f... (2016) Anti CD163+, Iba1+, and CD68+ Cells in the Adult Human Inner Ear: Normal Distribution of an Unappreciated Class of ...
潜伏期,海马组织Iba1阳性细胞数,IL-1β水平,CD68,iNOS,p-STAT3/STAT3,p-JAK2/JAK2表达显著减少(P<0.05).结论:DMY可能通过抑制JAK2/STAT3通路抑制小胶质细胞活化... 刘伟,方军,张抗抗 - 《中国免疫学杂志》 被引量: 0发表: 2023年 加载更多研究点推荐胃...
做的是背根神经节(DRG)的免疫荧光染色,按道理来说应该是类似小胶质细胞形态的,但是我染出来非常的巨大。 即便是研究巨噬细胞而非小胶质细胞反应的文献里,DRG里的CD68也应该如下图一样而非我做出来的形态。 这只抗体做脊髓染色的话是正常的小胶溶酶体形态。
Hendrickx, D.A.E.; van Eden, C.G.; Schuurman, K.G.; Hamann, J.; Huitinga, I. Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology.J. Neuroimmunol.2017,309, 12–22. [Google Scholar] [CrossRef] ...
分别采用机械缩足反射阈值(MWT)和热缩足反射潜伏期(TWL)评价大鼠机械痛敏和热痛敏;Western blotting 法和免疫荧光化学检测CSF-1 以及小胶质细胞标志物Iba1 表达;RT-PCR 法检测CSF-1 mRNA 和Iba1 mRNA 表达;ELISA 法检测TNF-α、...
对Iba1+细胞的Sholl分析显示,FD组中激活的小胶质细胞增加,表现为循环指数增加和分支指数降低(p<0.05;图3D,E)。此外,我们发现FD小鼠海马区促炎细胞因子、肿瘤坏死因子(TNF)-α、白细胞介素(IL)-6和IL-1β的水平增加(p<0.05,图3F),表明促炎M1激活。FD组小胶质细胞中CD68(吞噬标记物)的免疫荧光强度上调(图...
cells within the granule layer of the dentate gyrus but did not alter the overall temporal and regional pattern of Iba1 and CD68 staining within the cortex, periventricular white matter, fimbria, or thalamus.Debbie SmithDiane BrooksEric WohlgehagenThomas RauDavid Poulsen炎症(英文)...
Sections were immunohistochemically labelled with a two-round multiplexed antibody panel against; microglial functional markers (L-ferritin, HLA-DR, CD74, CD68, and Iba1), a neuronal marker, an astrocyte marker, and pathological phosphorylated TDP-43 (pTDP-43). Single-cell levels of microglial ...