NK细胞 (Natural Killer cells):自然杀伤细胞,是免疫系统中的重要细胞,能够直接识别并杀死肿瘤细胞和病毒感染细胞。 文章标题:Gene-modified NK cells expressing CD64 and preloaded with HIV-specific BNAbs target autologous HIV-1–infected CD4+ T cells by ADCC 作者:Costin Tomescu, Adiana Ochoa-Ortiz, Lil...
未来,这种“智能弹药库”型NK细胞或将成为对抗慢性感染与癌症的利器。 参考文献:Costin Tomescu, Adiana Ochoa-Ortiz, Lily D Lu, Hong Kong, James L Riley, Luis J Montaner, Gene-modified NK cells expressing CD64 and preloaded with HIV-specific BNAbs target autologous HIV-1–infected CD4+ T cells...
The CHO/Human CD64 Stable Cell Line was engineered to express full length human CD64 receptor (Gene ID: 2209), with different levels of CD64 expression (High, Medium, Low), which can be used to test agonist antibody whether in a CD64-dependent manner to strengthen the agonistic activity....
The Human CD64 (Luc) Jurkat Reporter Cell was engineered to not only express the NFAT response element driving luciferase expressing systems, but also express the receptor human CD64 (Gene ID: 2209), which can use to evaluate ADCP activity of antibodies in the presence of corresponding target ...
Entrez Gene ID:(Human) 2209 功能 receptor signaling protein activityprotein bindingIgG bindingimmunoglobulin receptor superfamily 参与通路 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentreceptor-mediated endocytosisphagocytosis, engulfmentimmune re...
CD64 (FCGR1A) encodes a protein that plays an important role in the immune response. CD64 is a high-affinity Fc-gamma receptor and is one of three related gene family members located on chromosome 1. CD64 plays an important role in the immune response and its dysfunction has been studied...
same approach to depression samples, we identified 571 upregulated and 847 downregulated genes. Furthermore, by intersecting these datasets, we extracted 121 upregulated and 175 downregulated co-DEGs. Through PPI network construction and hub gene selection, we identified MPO, ARG1, CD163, FCGR1A, ...
The CHO/Human CD64 Stable Cell Line was engineered to express full length human CD64 receptor (Gene ID: 2209), with different levels of CD64 expression (High, Medium, Low), which can be used to test agonist antibody whether in a CD64-dependent manner to strengthen the agonistic activity....
Long Name Fc gamma Receptor I Entrez Gene IDs 2209 (Human); 14129 (Mouse); 295279 (Rat); 102147198 (Cynomolgus Monkey) Alternate Names CD64 antigen; CD64; CD64a; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc gamma RI; FCG1; Fc-gamma receptor I B2; Fc-gamma RI; ...
Ernst, L.et al. (1998) Mol Immunol.35:943. Long Name Fc gamma Receptor I Entrez Gene IDs 2209 (Human); 14129 (Mouse); 295279 (Rat); 102147198 (Cynomolgus Monkey) Alternate Names CD64 antigen; CD64; CD64a; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc gamma RI; FC...