因此，将这群细胞命名为CD4+CD25+调节性T细胞（Treg）。目前，最常用的鉴别Tregs的标志Marker是CD4、CD25...
CD62L is another marker of nave T-cells. Depletion of CD62L+ cells may offer advantages of removing central memory T-cells which may also cause mild GVHD, and retain CD45RA+ effector memory T-cells (TEMRA). We aimed to evaluate the depletion efficiency, safety and immunoreconstitution ...
L-Selectin (CD62L, MEL-14, LAM1, SELL) is a cell adhesion molecule responsible for homing and mediating the binding of lymphocytes to high endothelial venules (HEV) in secondary lymphoid tissues (1-5). It is a commonly used marker for distinguishing naive and memory T ...
CD3 is expressed by a high-percentage of circulating peripheral T-cells and is considered a pan T-cell marker. Clone UCHT1 specifically recognizes the 20kDa CD3ε chain.The CD8 antigen is expressed on the human suppressor/cytotoxic T-lymphocyte subset (CD3+CD8+), as well as on a subset ...
CD44andCD62Lonspleenlymphocytesweredownregulatedaftercultureinvitroregardlesswithorwithoutstimulatingfactors,especiallyCD62L,almostdisappeared畅Thisshouldbegivenfullconsiderationwhenthesemarkersaredetectedaftercellculture.[Key words] Cellsurfacemarker;Mouse;Lymphocyte 细胞表面存在众多表面标记分子,可用以区分不同类型、不...
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On the other hand, expression by bovine T cells of CD62L, which is often used as a marker for Tcm in mice, was investigated on several occasions. Using OVA-immunized cattle it was shown that CD4+CD62L− and CD4+CD62L+ cells responded to OVA stimulation in vitro [6]. The ...
Cell surface marker staining and flow cytometry The isolated single cells from primary tumor, lung, PB or BM were washed with cell staining buffer for twice and then resuspend with 100 μl of cell staining buffer (Biolegend, #420201). Then fluorochrome-conjugated anti-mouse monoclonal antibod...
in contrast to humans in Rats CD45RA is a B-cell marker and we include it in the T-cell panel to exclude B-cells during analysis. In a similar way we included the T-cell marker CD3 in the B-cell panel. In the literature one marker used to characterise CD4+ T-cell differentiation ...
2.有一些marker可以表征这种动态变化过程 根据表型,功能及转录因子,目前CD8+T细胞可以进一步分为以下不同的亚群: Tnaive CD44-CD62+ T SCM :干细胞记忆T细胞(Stem cell memory T cell) T EM:效应记忆T细胞(Effector memory T Cell):CD44+CD62L-