Both eNK (endometrial NK cells) and dNK highly expressed IL-24 receptors (IL-20R1 and IL-22R1), especially on CD56dim eNK. However, there were extremely low levels of IL-20R1 and IL-22R1 on pNK. Recombinant human IL-24 or DSCs-secreted IL-24 downregulated the levels of CD16, ...
但近年越来越多的研究表明CD56 brightCD16 dimNK细胞亚型在肿瘤的生物学作用中扮演"帮凶"角色,现将近年关于CD56 brightCD16 dimNK细胞在在肿瘤中发挥的效应综述如下。 关键词: NK细胞;TINK;TANK;肿瘤;进展 ABSTRACT Natural Killer (NK) cells can directly kill target cells without pre-sensitization of ...
根据CD56和CD16表达,可以将NK细胞分为CD56bright和CD56dim,研究人员将不同来源的NK细胞CD56bright进行了lncRNA筛选检测。结果显示,CD56bright dNK, CD56bright pNK和 CD56bright cNK非常相似。其中,lncRNA AB128931在dNK和pNK细胞中高表达。生物信息学分析显示,AB128931的靶基因为CD56,来源于CD56的第一个内含子区域,...
increased ifn-γ production by nk and cd3 cd56 cells in sexually hiv-1-exposed but uninfected individuals 热度: 【word】 正常人外周血自然杀伤T细胞(CD3^+CD16^+CD56^+)比例 热度: 非小细胞肺癌患者CD8~+CD56~+NKT细胞亚群的特性研究 热度: ...
Functions of the CD16 dNK subset were shown to be independent of cellular interaction with trophoblast cells. Studies of preeclamptic patients revealed lower proportions of CD16 dNK cells, suggesting potential protective roles of these cells during normal gestations.. Therefore, we suggest that the ...
CD56pregnancyfetalIn early pregnancy,the decidua is populated by a large number of natural killer cells(NKs),most of which are CD56bright with a strong capacity to secrete cytokines,differing from peripheral and cord blood NK cells(pNKs and cNKs).1,2,3 It is generally believed that uterine ...
CD82CXC12deciduaNKtrophoblastsProblem: Decidual natural killer (dNK) cells play key roles in maternal-fetal immune regulation, trophoblast invasion, and vascular remodeling, and most dNK cell populations are CD56bright CD16- NK cells. However, the enrichment and redistribution of dNK cells in the ...
STUDY QUESTION Does glycodelin-A (GdA) induce conversion of human peripheral blood CD16(-)CD56(bright) natural killer (NK) cells to decidual NK (dNK) cells to facilitate placentation?Lee, Cheuk-LunVijayan, MadhaviWang, XiaLam, Kevin K. W.Koistinen, HannuSeppala, MarkkuLi, Raymond H. W...
CD29CD82CXC12deciduaNKtrophoblastsProblem Decidual natural killer (dNK) cells play key roles in maternal‐fetal immune regulation, trophoblast invasion, and vascular remodeling, and most dNK cell populations are CD56 bright CD16 ? NK cells. However, the enrichment and redistribution of dNK cells ...