本发明提出了确定是否出现空肠组织炎症反应或者确定所述炎症反应程度或变化的标志物,所述标志物选自促炎性巨噬细胞亚群CD45<Sup>+</Sup>CD11b<Sup>+</Sup>F4/80<Sup>+</Sup>CD14<Sup>+</Sup>。在发生空肠组织炎性反应后,促炎性巨噬细胞亚群CD45<Sup>+</Sup>CD11b<Sup>+</S
f4/80 + cd14 + 的占比(即促炎性巨噬细胞亚群cd45 + cd11b + f4/80 + cd14 + 在空肠组织所有巨噬细胞中的比例)出现了显著升高。由此,促炎性巨噬细胞亚群cd45 + cd11b + f4/80 + cd14 + 既可以作为确定是否出现空肠组织炎症反应的标志物,也可以通过降低促炎性巨噬细胞亚群cd45 + cd11b + f4/80...
These CD45intCD11bint MPCs were further identified as F4/80+MHCII+CX3CR1+Ly6C- cells, comprising ~17% of total CD45+ cells in normal mouse kidney (P < 0.01) and virtually absent from all other organs examined except the heart. Systemic clodronate treatment had more significant depletive...
在发生空肠组织炎性反应后,促炎性巨噬细胞亚群CD45+CD11b+F4/80+CD14+的占比(即促炎性巨噬细胞亚群CD45+CD11b+F4/80+CD14+在空肠组织所有巨噬细胞中的比例)出现了显著升高.由此,促炎性巨噬细胞亚群CD45+CD11b+F4/80+CD14+可以作为确定是否出现空肠组织炎症反应的标志物,尤其适用于60Coγ射线辐射所引发的...
这些CD45INTCD11b的INT的MPC进一步鉴定为F4 / 80+MHCII+CX3CR1+的Ly6C-细胞,其包含〜总CD45的17%+正常小鼠肾细胞(P除外<0.01),几乎不存在从所有其它器官检查心。全身性氯膦酸盐治疗对CD45有更显着的耗竭作用intCD11bint人群(77.3%±5.9%,P= 0.03)比CD45高CD11b+人群(14.8%±16.6%,P= 0.49)。另外...
小鼠脂肪组织巨噬细胞同样可以用CD11b+、F4/80+作为标志物,但是F4/80mid群包含嗜酸性粒细胞 (Siglec-F+) 和中性粒细胞(GR1+),因此,圈门的时候要十分小心,只要圈下图中1门的位置,进一步可以通过CD11c+和CD301+/CD206+去区分M1...
由此,促炎性巨噬细胞亚群CD45+CD11b+F480+CD14+可以作为确定是否出现空肠组织炎症反应的标志物,尤其适用于60Coγ射线辐射所引发的空肠组织炎症反应。 专利权项:1.一种确定是否出现空肠组织炎症反应或者确定所述炎症反应程度或变化的标志物,其特征在于,所述标志物选自促炎性巨噬细胞亚群CD45+CD11b+F480+CD14+。
CXCL17 Expression by Tumor Cells Recruits CD11b+Gr1highF4/80 Cells and Promotes Tumor Progression Chemokines are involved in multiple aspects of pathogenesis and cellular trafficking in tumorigenesis. In this study, we report that the latest member of t... M Aya,Y Hideaki,N Yoichi,... - 《...
(London, England)December 1, 2023Qi D, Lu M, Xu P, Yao X, Chen Y, Gan L, Li Y, Cui Y, Tong X, Liu S,et al.Subsequently, the cells were stained with anti‐CD68 (137009, FA‐11), anti‐F4/80(123110, BM8), anti‐CD45(103115, 30‐F11), anti‐CD11b(101212, M1/70), ...
Further studies using Fc receptor blockers disclosed that this population was a renal macrophage subset which was different from other macrophages by its intermediate expression of CD45 and CD11b. These CD45intCD11bint macrophages were further characterized as F4/80+MHCII+Ly6C cells comprising 40%...