1. 小鼠血液 在小鼠血液中,巨噬细胞也可以叫做Ly-6Clow单核细胞,含量较少,一般用CD11b+、F4/80+作为检测标志物。 2. 小鼠骨髓 巨噬细胞也一般用CD11b+、F4/80+作为检测标志物。 3. 小鼠肝脏组织 小鼠肝脏中有两类巨噬细胞...
CD11b(+)CD45(+)Brain tumorGR1MDSCGlioblastoma multiforme is characterized by high accumulation of microglia/macrophages. The function of these tumor-infiltrating myeloid cells is not sufficiently elucidated. Therefore, a better understanding of the precise immune cell composition and function in brain ...
Myeloid-derived suppressor cells (MDSCs) are a prominent component of the pro-tumoral response. The phenotype of and mechanisms used by MDSCs is heterogeneous and requires more precise characterization in gastric cancer (GC) patients. Here, we have identified a novel subset of CD45+CD33lowCD11b...
(B–F) Myeloid (CD11b+/Gr1+), B lymphoid (B220+), T lymphoid (CD4+/CD8+), Erythroid (Ter119+), and megakaryocyte (FSCHi CD41+) lineage potential of sorted iTdTomato+ CD44+ CD51– TNCs (B), CD44– CD51– TNCs (C), CFU-E (D) preCFU-E (E), and preMegE (F). Cell num...
They are slightly bigger than normal B cells (as detected by forward scatter using flow cytometer) and also express CD43, CD11b, and Gr1 antigens (data not shown). These cells may represent an unusual myeloid cell population. We excluded this population from the B cell gate based on ...
Microglia are CD11b � CD45 low , macrophages are CD11b � CD45 high , granulocytes are CD11b � CD45 high Gr1 high =-=(39)-=-. Control staining was performed with isotype-matched control Abs. Flow cytometry was performed on a FACScan (BD Biosciences), and the data were analyzed...
To selectively analyse microglial reactions in TE, we have established a model of radiation-induced CD45-congenic bone marrow chimeras between CD45.2 + C57BL/6 (recipient) and CD45.1 + B6.SJL (donor) mice. These chimeras allow a differentiation of radioresistant CD45.2 + microglia from all ...