Human T cell leukemia lymphoma virus type I (HTLV-I) associated T cell lines derived from peripheral blood leukocytes of patients with adult T cell leukernia/ lymphoma (ATL/L) in Japan did not express CD45 on their cell surface. Taken together, these observations suggest that CD45 has a ...
Flow cytometry of CD45 depleted leukocytes Additional granulocyte depletion efficiency 文件和下载 证书 搜索 批号Certificate TypeDateCatalog Number(s) 3166524Certificate of Analysis2025年2月11日11153D 2807008Certificate of Analysis2025年1月29日11153D ...
The monoclonal antibody 104-2 recognizes CD45 (Leukocyte Common Antigen) on all leukocytes of mouse strains expressing the CD45.2 allotype (e.g. A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). ...
CD45 is leukocyte specific, expressed on all hematopoietic cells except red blood cells and this has led to the clinical use of pan-specific CD45 mAbs to identify leukocytes and cells of hematopoietic origin. Some mAbs identify specific isoforms of CD45 that are expressed in a cell type and ...
Lck . In other leukocytes, CD45 influences differentiation and links immunoreceptor signaling with cytokine secretion and cell survival, partially overlapping in function with DEP-1/CD148. CD45 deletion causes in severe immunodeficiency, while point mutations may be associated with autoimmune disorders ....
CD45 a major component of the lymphocyte membrane is present on the surface of all human leukocytes, lymphocytes, eosinophils, monocytes, basophils, and neutrophils. In addition, CD45 antibodies react with the leukocyte progenitors found in bone marrow. CD45 is lost during maturation of erythroid ...
Easily isolate highly purified mouse CD45+ tumor-infiltrating leukocytes (TILs) by immunomagnetic positive selection using the EasySep™ Mouse TIL (CD45) Positive Selection Kit. This kit has been optimized for use on single-cell suspensions of solid mouse tumors, including tumors induced by implant...
CD45E6 À / À have significantly reduced numbers of T cells in the spleen and periphery and CD45E9 À / À mice have even less T cells compared with wild-type (WT) mice.4,5,7 Although most leukocytes are negative for CD45, in the CD45E6 À / À mice, a small ...
mAb A20 has been reported not to react with leukocytes of most other mouse strains, which express the CD45.2 alloantigen. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region...
making it a useful marker for identifying leukocytes in flow cytometry experiments. The APC conjugate allows for easy detection of CD45-positive cells in a flow cytometry setting. This antibody is intended for research use only and should be stored at 2-8°C.在选择BioLegend APC anti-human CD...