Code Anti-hCD40L-IgG Anti-hIL-1β-IgG Anti-hTNF-α-hIgG1 Blasticidin Normocin™ QUANTI-Blue™ Solution Recombinant human CD40L Recombinant human IL-4 Zeocin® Neutralizing antibody mabg-h40l-3 Neutralizing antibody mabg-hil1b-3 Neutralizing antibody ...
CD40L, as expected, stained strongly on CD4+ T cells (Figure 2A), compared with either Cd40lg−/− controls (Figure 2A) or with control antibody staining (data not shown). CD8+ T cells showed virtually no staining of CD40L (Figure 2B). We found that CD40L was also expressed quite ...
CD40L participates in chronic inflammatory diseases such as atherosclerosis. Through interaction with its classic receptor CD40, CD40L regulates B-cell and T-cell function. CD40L also stabilizes thrombi through interaction with the platelet integrin αIIbβ3. While anti-CD40L antibody treatment generated...
CalDAG-GEFI deficiency protects mice from Fc gamma RIIa-mediated thrombotic thrombocytopenia induced by CD40L and beta 2GPI immune complexesantigen-antibody complexIgGplatelet activationreceptorsthrombocytopeniathrombosisIntroductionPlatelet activation via the Fc receptor IIa (FcRIIa) is implicated in the ...
-linked and non-X-linked forms of HIM syndrome and discuss the critical role the CD40∶CD40L receptor-ligand pair play in the pathogenesis of these immune deficiencies.
MiR-7 deficiency promotes Th1 polarization of CD4+T cells and enhances the antitumor effect in adoptive cell therapy for lung cancer Article 27 September 2023 Production of an interleukin-10 blocking antibody by genetically engineered macrophages increases cancer cell death in human gastrointestinal tu...
During chronic AdVova infection, mouse CTLs were found to express the inhibitory molecules programmed cell-death protein-1 (PD-1) and lymphocyte-activation gene-3 (LAG-3) and to be functionally exhausted, showing a significant deficiency in T-cell proliferation, IFN-γ production and cytolytic ...