Lawn SD, Myer L, Bekker LG, Wood R (2006) CD4 cell count recovery among HIV-infected patients with very advanced immunodeficiency commencing antiretroviral treatment in sub-Saharan Africa . BMC Infect Dis 6 : 59. 10.1186/1471-2334-6-59...
● 免疫细胞图谱构建:研究发现INRs中存在显著的CD4+ T细胞比例减少与干扰素信号通路异常激活。进一步的CD4+ T细胞分群结果显示,INRs的初始CD4+ T细胞显著减少,且耗竭表型CD4+ T细胞显著增加。 ● 干扰素信号通路激活:通过VILDA工具,研究发现INRs体内HI...
Bray S, Gedeon J, Hadi A, et al. Predictive value of CD4 cell count nadir on long-term mortality in HIV-positive patients in Uganda.HIV AIDS (Auckl). 2012;4:135–140. doi:10.2147/HIV.S35374 National Institute of Allergy and ...
The odds of getting incident TB was 2.88 (95% CI; 1.55–5.35%) for patients with baseline CD4+ T cell count < 200 cells/mm3 compared to patients with baseline CD4+ T cell count > 200 cells/mm3. Conclusion: High incident TB among adult HIV positive patients was estimated, especially in...
Low CD4+ cell count in patients with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) coinfection during combination antiretroviral therapy (cART) has been described; however, notably few studies have investigated coinfected patients positi
Chronic immune activationhas been considered asthe driving force for CD4+ T cell depletion in people infected with HIV-1. 艾滋病毒核酸检测结果是阴性不是人员没有Chronic immune activation(长期/慢性免疫系统免疫能力异常)触发的CD4+ T细胞消失,不是免疫系统免疫能力消失。
If therapy is interrupted in treated non-EC patients, HIV viremia rebounds, demonstrating that anti-HIV therapy is not curative. We show here that therapy removes the bulk of HIV-specific immune cell alterations while controlling IFNα levels, as seen in ECs; however, some residual alterations ...
(CDC) stage, immunological and virological status (viral load and CD4 T-cell count) of HIV infection as well as information on ART (date of initiation, com- bination of drug classes in therapy regimes, therapy interruption) are recorded upon enrolment and updated for every date in which the...
In brief, IR (immunological responder) and INR (immunological non-responder) were defined as HIV-patients whose CD4 + T cell count > 350/mm3 and < 350/mm3 after at least two years of ART, respectively. For the samples collected, i.e., after two years of ART, we found no significant...
(1.3%). Trend analysis of coccidian aetiology during the study period revealed a significant rise in the positivity of C. belli and Cryptosporidium spp. (P = 0.001). Among the HIV patients with CD4+ T-cell counts <200 cells/μL, Cryptosporidium infection was most common (90%), followed ...