Thus, within the limits of resolution of this method, the T-cell and the BM form of CD4 appear to be identical. Download: Download full-size image Fig 3. CD4 molecules in BM and thymus. The CD4 molecule was precipitated with GK1.5-conjugated Sepharose from biotinylated cell preparations and...
Medical Encyclopedia Related to CD4 antigen:CD4+ cell CD4 (sē′dē-fôr′) n. A glycoprotein that is found on the surface of T cells, especially helper T cells, and functions as a receptor in activation of the cells. In humans, HIV gains entry to helper T cells by binding to the ...
Here, we report that in the human system, CD4+T cells use not only CD40L but also IFNβ to license cDC1s for the induction of antitumor immunity. In general, myeloid cells, rather than lymphocytes, are thought to be the main producers of type I interferon (IFN-I) upon stimulation by ...
et al. Requirement of full TCR repertoire for regulatory T cells to maintain intestinal homeostasis. Proc. Natl. Acad. Sci. USA 112, 12770–12775 (2015). 62. Wang, L. et al. T regulatory cells and B cells cooperate to form a regulatory loop that maintains gut homeostasis and suppresses ...
Download: Download full-size image Figure 4. Recombinant Fusin Is Sufficient to Render U87 Cells Susceptible to HIV-2/vcp Syncytium Induction and Infection (A) Syncytium induction assays. U87 cells stably expressing either Fusin or CD4, or untransduced cells (control) were cocultured with HIV...
Author Contributions: Dr Rodríguez had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Rodríguez, Sethi, Cheruvu, Kitahata, Deeks, Lederman. Acquisition of data: Rodríguez, ...
Full size image To determine the differentiation phenotype of BTLA+CD4+T cells, we examined the frequencies of the subtypes of effector memory cells re-expressing CD45RA (TEM-RA), Tnaive, central memory (Tcm), and effector memory (Tem) of BTLA+CD4+T cells and BTLA-CD4+T cells in pe...
Different data collection strategies were used in the HIV-BCS cohort study: phase 1 –retrospective cohort– a standardized form was applied on patient medical reports and data entered onto a specific EpiData 3.1 form (The EpiData Association, Odense, Denmark); phase 2 – prospective cohort – ...
Show full outline Cited by (212) Figures (14) Show 8 more figures Tables (1) Table Extras (8) Download all Table S1. The transcriptome of CD4+ or CD8+ T cells isolated from NT and ES-treated mice, Related to Figures 2A–2D Table S2. PLS-DA of metabolomic profile in the serum...
Download: Download full-size image Fig. 2. In unimmunized animals HEL-specific T cells are present in the naïve, regulatory, effector memory, and central memory T cell compartments. (A) Splenocytes from antigen-naïve, 12-to-14-week-old BALB/c mice were FACS sorted to isolate naï...