Definition A measure of the concentration in blood of CD4 antigen-positive T-lymphocytes. This is the most commonly used measure of the effect of HIV infection on the immune system. CD4 counts below 200 cells per μL are associated with increased risk of AIDS ....
The CD4 cell count of a person who does not have HIV can be anything between 500 and 1500. People living with HIV who have a CD4 count over 500 are usually in pretty good health. People living with HIV who have a CD4 cell count below 200 are at high risk of developing serious illnes...
Things other than the HIV virus can influence how high or low your CD4 count is. An infection like the flu, pneumonia, or aherpes simplex virus(includingcold sores) can make your CD4 count go down for a while. Your CD4 count will go way down when you're havingchemotherapyforcancer. Eve...
In view of the expected slow rate of decline of the CD4 + cell count, it is not surprising that the estimated mean duration of survival from time of onset of HIV infection to death in patients receiving standard preventive therapies (as described below), is more than 10 years, even in th...
A CD4 count below 200 indicates serious immune damage. It is a sign of AIDS in people with HIV infection. Although the CD4% may be a better predictor of HIV disease progression than the CD4 count, the CD4 count is used to decide when to start treatment. ...
Sometimes, CD4 tests may be used to help diagnose or monitor other conditions such as lymphoma, organ transplantation, and DiGeorge syndrome (see below). When is it ordered? A CD4 count is usually ordered along with anHIV viral loadwhen you are first diagnosed with HIV infection as part of...
Allogeneic bone marrow transplantation can restore CD4+ T-lymphocyte count and immune function in idiopathic CD4 + T-lymphocytopenia. Bone Marrow Transplant. 1996;18:813–815. 114. Cervera C, Fernandez-Aviles F, de la Calle-martin O, et al. Non- myeloablative hematopoietic stem cell ...
Although the screening CD4 cell count had to be 200 cells/μL or less within 90 days of enrollment there was no restriction on the baseline CD4 cell count (obtained from a sample drawn at the time of treatment initiation). 47 women had screening CD4 count <200 cells/μL but enrollment ...
doctor may consider ART (antiretrovial therapy) although this depends on other factors. As your CD 4 count falls below 500, a fluctuation may be considered significant as ART may be started when your CD4 cell count falls below 350 cells/mm3 (in some countries if it is below 200 cells/...
Dutch ATHENA cohort members with a CD4 count under 200 when they entered the cohort had more new cardiovascular and non-AIDS cancer diagnoses than people with higher initial CD4 counts [1]. Older age, lower nadir (lowest-ever) CD4 count, and use of a nonnucleoside (NNRTI)-based regimen pr...