AlekseyV. Belikov. The role of reactive oxygen species and mitochondria in T-cellactivation. (图1) YoshihiroOhue,Hiroyoshi Nishikawa. Regulatory T (Treg) cells in cancer: Can Treg cellsbe a new therapeutic target? Cancer Sci. 2019 Jul;110(7):2080-2089.(图2) 作者:奇 诺 本文首发于“ 解...
当然,除了CD8+T细胞,其他T细胞亚型,比如CD4+T细胞以及其亚类调节性T细胞(regulatory T cells,简称Tregs)在TCC发生发展中的作用,以及对靶向PD-1的免疫治疗效果的影响,仍旧不得而知。 近日,来自美国加州大学的Chun Jimmie Ye和Lawrence Fong研究组在Cell杂志上发表题为Intratumoral CD4 T Cells Mediate Anti-tumor Cytot...
Immunology Regulatory T cells in CD4+ T cell-mediated autoimmune diseases| Contribution to the disease development and application in the disease prevention NORTHWESTERN UNIVERSITY Stephen D. Miller ZhangHongCD4T cells play a critical role in the maintenance of homeostasis through generating distinct ...
近日,Tuberculosis 杂志发表了一项胸膜结核瘤患者CD4+调节性T细胞(Treg)的表达及调节CD4+T淋巴细胞活化的研究(Gao W, Yang N, Ji S, Zeng Y. Frequency of CD4+ regulatory T cells and modulation of CD4+T lymphocyte activation ...
Mojgan Ahmadzadeh, Anna Pasetto, Li Jia1, Drew C. Deniger, Sanja Stevanović,Paul F. Robbins, Steven A. Rosenberg.Tumor-infiltrating human CD4 regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity.Sci. Immunol. 4, eaao4310 (2019) ...
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1.Lin H, Xu Y and Lin C (2024) Heterogeneity and subtypes of CD4 regulatory T cells: implications for tumor therapy. Front. Immunol. 14:1291796. doi: 10.3389/fimmu.2023.1291796+ 2.LIU Xindong, WU Xin.Molecular cues govern follicular regulatory T cell differentiation.Journal of Third Military...
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