CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets. Blood, 123 (19) (2014), pp. 3016-3026 Google Scholar 15 AS Chretien, A Le Roy, N Vey, et al. Cancer-induced alterations of NK-mediated target recognition: current and invest...
with emphasis on their heterogeneous phenotypes and mechanisms of action. In humans, myeloid-derived suppressor cells (MDSCs) are broadly classified as either neutrophilic or MO MDSCs, and are phenotypically
with emphasis on their heterogeneous phenotypes and mechanisms of action. In humans, myeloid-derived suppressor cells (MDSCs) are broadly classified as either neutrophilic or MO MDSCs, and are phenotypically
Results Characterization of sorted tumor‑infiltrating CD33+ myeloid cells in CRC patients CD33 is expressed on a heterogenous population of mye- loid cells, and it does not distinguish MDSCs from TAMs or tumor-associated neutrophils (TANs) [20]. In addition, CD33 can be expressed on...
CD14+CD15-HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure CD14+CD15CD11b+HLA-DR cells were identified as per definition of M-MDSC and detailed immunophenotypic analyses were performed. Suppression of T cell activation was assess...