Low density of CD3+ cells at the invasion front and increased risk of liver metastases development in microsatellite-stable colorectal cancer patients / E. Miranda, E. Balladore, P. Bianchi, A. Mantovani, A. Malesci, M. Roncalli, L. Laghi. - In: Gastroenterology. - ISSN 0016-5085. - ...
Low density of CD3+, CD4+ and CD8+ cells is associated with increased risk of relapse in squamous cell cervical cancer. Br J Cancer 2007; 97 : ... B Nedergaard,M Ladekarl,HF Thomsen,... - Low Density of Cd3+, Cd4+ & Cd8+ Cells Is Associated with Increased Risk of Relapse in Squ...
We used flow cytometry to identify the presence of intracellular cytokines (cytoflow) and analyse the production of IL-4 in peripheral blood from AIDS patients who have practically no CD4+ T cells. We found that IL-4 was produced by CD3−CD4−CD8−CD56−CD19−CD14− cells and CD3...
We studied the induction, severity and rate of progression of inflammatory bowel disease (IBD) induced in SCID mice by the adoptive transfer of low numbers... M Claesson - 《Journal of Immunology》 被引量: 174发表: 1999年 CD133+ Anaplastic Thyroid Cancer Cells Initiate Tumors in Immunodeficien...
- 1995 - A1162 - www.sciencedirect.comdoi:10.1016/0016-5085(95)28948-8NoneGastroenterology
Intraductal carcinoma of the prostate is characterized by prostatic carcinoma cells growing within ducts and/or acini. These tumors are usually associated ... T Tsuzuki - 《International Journal of Urology Official Journal of the Japanese Urological Association》 被引量: 23发表: 2015年 Intraductal car...
type (WT)/CD8+/+ or CD8α/KO backgrounds, a CD8α Tg directed by cis-mechanism I alone is activated during the double negative [DN] to double positive [DP] transition and expressed up to the CD3low/intermediateDP stage but not in more mature DP or SP thymocytes or peripheral T cells...
Decrease in CD3-negative-CD8dim(+) and Vdelta2/Vgamma9 TcR+ peripheral blood lymphocyte counts, low perforin expression and the impairment of natural kille... percentage of CD3(-)CD8+, Vgamma9/Vdelta2 TcR+ and perforin-positive T cells and simultaneous decreased peripheral NK activity may ...
We have reported previously that carrying > 30 copies of the CD3 transgene completely lose their T lymphocytes and NK cells (36). Here we demonstrate by immunohistology that in the most severely immunodeficient , tg 26, the thymus is very small, has sizeable and does not contain recognizable...
Vγ2Vδ2 T cell-based immunotherapy has benefited some patients in clinical trials, but the overall efficacy is low for solid tumor patients. In this study, a bispecific antibody against both PD-L1 and CD3 (PD-L1 x CD3), Y111, could efficiently bridge T cells and PD-L1 expressing tumor...