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Domain antibodies that are monovalent for binding of CD28 can inhibit CD28 activity. In one aspect, a domain antibody consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of CD28, in an aspect, without substantially agonizing CD28 ...
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. T cell activation through the TCR can result in either cell proliferation or cell death. The role of costimulatory receptors in regulating T cell survival ... Boise, L. H,Minn, A. J,Noel, P. J,... ...
T-cell senescence, characterized by expansion of cells lacking the costimulatory molecule CD28, has been hypothesized to mediate these risks. METHODS: We measured the percentage of CD28(-)CD4(+) and CD8(+) T cells from HIV-infected treatment-naive adults from 5 Adult Clinical Trials Group (...
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CC220 抗原 Plasmid DNA encoding the bovine CD28 gene 偶联物 Unconjugated 形式 Liquid 浓度 1 mg/mL 纯化类型 Protein A 保存液 PBS 内含物 no preservative 保存条件 -20°C 运输条件 Ambient (domestic); Wet ice (international) RRID AB_2745304 产品详细信息 Mouse anti...
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Repeated antigen-driven proliferations cause CD28 on T cells to down-regulate. We hypothesized that alloantigen-induced proliferations could cause CD28 down-regulation in lung transplant recipients. To ascertain if CD28 down-regulation on CD4 T cells associated with manifestations of allograft dysfunction...
CD28/CTLA-4 and CD80/CD86 costimulatory molecules are mainly involved in acceptance or rejection of human liver transplant A,Marin L,Torio A,et al.CD28/CTLA-4 and CD80/CD86 costimulatory molecules are mainly involved in acceptance or rejection of human liver transplant. Hum... Alfredo Minguela ...
产品名称: 小鼠CD28分子(CD28)elisa检测试剂盒 产品规格: 96T 有效成分含量: 100 检测方法: 酶联免疫法 样本: 血清,血浆,尿液等生物样本 保质期: 6个月 标记物: HRP标记物 储存条件: 2-8℃冷藏 用途范围: 本试剂盒只能用于科学研究,不得用于医学诊断 是否进口: 否 英文代号: (CD28)elisa试...