It mentions impact of PDCD1 (PD-1)-positive tumour infiltrating T-lymphocytes (TILs) and CD274 (PD-L1)-positive macrophages and single antibody for CD274. It also mentions immunohistochemical detection of CD274 in macrophages or the lymphoma cells and paraffin-embedded (FFPE) ...
英文名称:CD274 (Programmed Cell Death 1 Ligand 1, PD-L1, PDCD1 Ligand 1, Programmed Death Ligand 1, B7 Homolog 1, B7-H1, CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1) 英文同义词:CD274 (Programmed Cell Death 1 Ligand 1, PD-L1, PDCD1 Ligand 1, Programmed Death Ligand 1, B7 Homolog 1...
CD274 (Programmed Cell Death 1 Ligand 1, PD-L1, PDCD1 Ligand 1, Programmed Death Ligand 1, B7 Homolog 1, B7-H1, CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1) 中文名: 中文别名: CBNumber: CB04967664 分子式: 分子量: 0 MOL File:
基因别名:A530045L16Rik; B7-H; B7H1; CD274; PD-L1; PDCD1L1; PDCD1LG1; PDL1 UniProt ID:(Human) Q9NZQ7,(Mouse) Q9EP73 Entrez Gene ID:(Human) 29126,(Mouse) 60533 功能 protein bindingimmunoglobulin receptor superfamily 参与通路 immune responsesignal trans...
Amplifications of PD-L1(CD274) and PD-L2 (PDCD1LG2) in a Large Cohort of Solid Tumors and Hematologic Malignancies Introduction: The PD-1/PD-L1/PD-L2 pathway is a critical tumor immune checkpoint and an emerging therapeutic target. The anti-PD-1 monoclonal antibodies, nivolumab and pembroliz...
该PD-L1, Recombinant, Human, aa19-239, FLAG-tag (CD274, Programmed Cell Death 1 Ligand 1, CD274 and B7 Homolog 1, B7-H1, PDCD1 Ligand 1, Programmed Death Ligand 1, PDCD1L1)产品的产品序列,详细查看产品说明书。 来源宿主 提供的PD-L1, Recombinant, Human, aa19-239, FLAG-tag (CD274,...
(CD274 molecule) 程序性死亡配体1(PD-L1)也称为分化簇274(CD274)或B7同源物1(B7-H1)是人类中由CD274基因编码的蛋白质。 程序性死亡配体1(PD-L1)是一种40kDa的1型跨膜蛋白,据推测其在特定事件如妊娠,组织同种异体移植,自身免疫性疾病和其他疾病状态如肝炎中在抑制免疫系统中起主要作用。 通常,免疫系统对与...
Background: The CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint interaction may promote cancer progression, but the expression patterns and prognostic significance of PD-L1 and PD-1 in the colorectal cancer microenvironment are inadequately characterised. Methods: We used a custom 9-plex ...
NSCLC carriers of rs11568821 T allele had almost double the risk of death (adjusted HR=2.05; 95% CI=1.28, 3.29;P=0.003) compared to carriers of CC genotype.#Our results provided additional evidence that SNPs of genes for PD-1, PD-L1 and TIM-3 differentially modulate the risk and ...
蛋白别名: B7 homolog 1; B7-H1; CD274; CD274 antigen; PD-L1; PDCD1 ligand 1; pdl-1; Programmed cell death 1 ligand 1; sCD274; soluble CD274; soluble PD L1; sPD L1 基因别名: B7-H; B7H1; CD274; PD-L1; PDCD1L1; PDCD1LG1; PDL1 UniProt ID...