Raggi F, Pelassa S, Pierobon D et al. Regulation of Human Macrophage M1–M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1. Front Immunol. 2017; 8: 1097.小鼠的巨噬细胞检测，也可以参考此方法，加上F4/80和CD11b作为上级门，圈出总的巨噬细胞。
and stimulate angiogenesis and invasion of tissues.M2 macrophages are predominant.CD206 is a M2 macrophage marker with high specificity and plays an important role in tumor cell proliferation and metastasis.Studies have shown that CD206 is closely related to malignant tumors such as breast cancer,...
plays an important role in immune defense and immune regulation. A soluble form of CD206 is generated by cleavage of the full-length protein, and it can be detected in in vitro macrophage cell culture supernatants and in mouse serum. CD206 is considered to be one of the markers of M2 mac...
巨噬细胞可以存在两种不同的表型,即促炎(M1)和抗炎(M2)表型。因此,将巨噬细胞从M1表型转换为M2表型是治疗炎症的一种潜在方法。通常通过对M1(iNOS,红色)和M2(CD206,绿色)标记物进行免疫荧光染色来评估巨噬细胞的表型变化。图1可以看出在FA-AgNPs处理后,iNOS(M1标志物...
Macrophage Mannose Receptor Entrez Gene IDs 4360 (Human); 17533 (Mouse); 291327 (Rat) Alternate Names CD206; CLEC13D; CLEC13Dmacrophage mannose receptor 1; C-type lectin domain family 13 member D; mannose receptor, C type 1; MMR; MMRCD206 antigen; MRC1 ...
CD206, CLEC13D, Macrophage mannose receptor 1, mannose receptor, C type 1, MMR, MRC1 Formulation: PBS and Azide PBS and Azide Conjugate: CoraLite® Plus 488 Unconjugated CoraLite® Plus 488 Size: 100 μL ¥3200/ 100 μL 浓度: 1000 μg/ml 库存:1-2周货期 收藏 点击咨询售前...
M2 macrophage marker CD206 and tumor 引用 收藏 分享 摘要 肿瘤相关巨噬细胞存在于肿瘤进展的所有阶段,起到促进血管生成、组织侵袭等作用,其中以M2型巨噬细胞居多。CD206是M2型巨噬细胞标志物,具有高度特异性,与肿瘤细胞的增殖和转移密不可分。已有研究表明CD206与乳腺癌、卵巢...展开更多 Tumor-associated ...
有两大类肿瘤相关巨噬细胞(tumor-associated macrophage, TAM):M1和M2。M1巨噬细胞吞噬细菌、病毒和癌细胞,并引起炎症。M2巨噬细胞促进组织从炎症中恢复过来。当M2巨噬细胞无法正常工作时,慢性炎症会导致诸如纤维化之类的疾病。纤维化是因胶原蛋白过度表达而导致的结缔组织沉积。
repairing, we looked for a specific marker for M2-like ATMs. We have previously shown that the vast majority of ATMs are CD206 + M2-like macrophages, but the ratio of CD206 + M2-like macrophages in F4/80-positive macrophage and F4/80-negative non-macrophage populations was not evaluate...
A soluble form of CD206 is generated by cleavage of the full-length protein, and it can be detected in in vitro macrophage cell culture supernatants and in mouse serum. CD206 is considered to be one of the markers of M2 macrophages. Factors inducing its expression include: IL-4, IL...