We present a unique case of primary breast CD20-positive extranodal NK/T cell lymphoma with stomach involvement in a young Chinese female patient.#The patient presented with a mass in her right breast that rapidly increased in size over approximately 2months. Upper gastrointestinal endoscopy showed ...
The presence of T cells that are dimly positive for the B cell marker CD20 is well-established in autoimmunity and correlates with disease severity in various diseases. Further, we previously identified that the level of CD20-positive T cells was three–fourfold elevated in ascites fluid of ovari...
CD20 positive peripheral T cell lymphoma unspecified: a case report淋巴瘤,非霍奇金抗原,CD20病例报告[文献类型]患者男,81岁.左足背复发性溃疡8年,渐累及双下肢.各系统检查未见异常.皮肤科检查: 左足背红肿,约7 cm×10 cm范围的皮肤溃疡面,基底部可见肌腱,皮损周围皮肤呈紫褐色,边缘堤状隆起;右足内缘可见...
It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type. 应用类型 Flow, IF...
Utilization of antibodies to deliver highly potent cytotoxic agents to corresponding antigen-overexpressed tumor cells is a clinically validated therapeutic strategy. Ofatumumab (OFA, trade name Arzerra) is a fully human CD20-specific antibody that is active against CD20-positive B-cell lymphoma/chronic ...
Based on these animal models, DI-Leu16-IL-2 could offer therapeutic potential for patients with CD20 positive lymphoma. Clinical trials are currently under development.Previous article in issue Next article in issue Introduction Non-Hodgkin lymphomas (NHLs) continue to present a significant clinical ...
31.Withoff,S.et al.Characterization of BIS20x3,a bi-specific antibodyactivating and retargeting T-cells to CD20-positive B-cells.Br.J.Cancer 84,1115-1121(2001). 32.Goldenberg,D.M.et al.Properties and structure-functionrelationships of veltuzumab (hA20),a humanized anti-CD20 monoclonalantibod...
CD30-positive atypical lymphoid cells in common non-neoplastic cutaneous infiltrates rich in neutrophils and eosinophils. CD30-positive cells characterize lymphomatoid papulosis and anaplastic large cell lymphoma but can also be found in nonneoplastic skin disorders. Purported... LT Cepeda,M Pieretti,SF...
Triple staining with anti‐TCRαβ (blue) and anti‐MHC II (red) revealed that TORID‐positive cells (green) predominantly localized in the red pulp, and to a lesser extent, in the periarteriolar lymphoid sheath (PALS), in the marginal zones, and B‐cell follicles in particular (Figure ...
CD20CAR-T cells also demonstrated significant lytic activity against CD20-downregulated tumor cells and may exhibit effectiveness for CD20-positive lymphoid malignancies. Copyright 2014 by The American Association of Immunologists, Inc. 展开 DOI: 10.4049/jimmunol.1402346 被引量: 46 ...