The role of CD5(+) B cells in patients with HCV infection and HCV-related disorders, including mixed cryoglobulinemia (MC), has been addressed in previous reports with conflicting results. We established a correlation between CD5/CD20 expression on circulating B lymphocytes, characterizing monoclonal...
CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation. CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells. CD20 expression on B cells is...
CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation. CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing...
Reoccurrence of the CD20 molecule expression subsequent to CD20negative relapse in diffuse large Bcell lymphoma. Haematologica 2007;92:e12.6. Hiraga J, Tomita A, Sugimoto T, Shimada K, Ito M, Nakamura S, et al. Downregulation of CD20 expression in Bcell lymphoma cells after treatment with ...
CD20 expression in normal canine B cells and in canine non-Hodgkin lymphoma. We examined the expression of CD20 in normal canine peripheral blood mononuclear cells, normal canine spleen, and canine non-Hodgkin lymphoma (NHL) to dete... C,M,Jubala,... - 《Veterinary Pathology》 被引量: 72...
长春新碱、和泼尼松联合使用;第二代抗CD20单抗包括Ofatumumab、Veltuzumab和Ocrelizumab等,降低了第一代抗体的免疫原性,如Ofatumumab能有效诱导利妥昔单抗抵抗的细胞和CD20低表达的恶性B细胞的补体依赖性细胞毒性;第三代单抗奥滨尤妥珠Obinutuzumab,通过糖基化修饰抗体Fc片段,增强靶点结合力,使得ADCC效应增强 [13-15]。
CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation. CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells. CD20 expression on B cells is...
CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation. CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells. CD20 expression on B cells is...
The RS-H cells in five cases expressed the B-lineage marker CD20 and were negative for CD15. In two cases, the RS-H cells showed expression of ... H Momose,ES Jaffe,SS Shin,... - 《American Journal of Surgical Pathology》 被引量: 374发表: 1992年 Rituximab induces remission in refra...
HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells Anti-CD20 antibody rituximab is now essential for the treatment of CD20-positive B-cell lymphomas. Decreased expression of CD20 is one of the major mechani... R Shimizu,J Kikuchi,T Wada,......