CD1C是一种转膜蛋白,属于免疫球蛋白超家族的一员,它在人类免疫系统中发挥着重要的作用。 CD1C属于CD1家族,包括CD1A、CD1B、CD1C和CD1D四个亚型,它们在免疫系统中都扮演着不同的角色。与其他CD1家族成员不同的是,CD1C主要表达在树突状细胞(dendritic cells,DCs)和B细胞上。DCs是一类免疫细胞,能够与T细胞相互...
CD1c(BDCA-1)+树突细胞分离试剂盒开发用于从PBMC分离CD1c(BDCA-1)+髓样树突细胞(MDC; 1型MDC或cDC2)。这种新的形式允许有选择地去除最近已经显示可能会污染最终DC群体的CD14+骨髓细胞。 CD1c(BDCA-1)抗原在树突细胞上特异性表达,并且CD11chighCD123low代表人血液中骨髓树突细胞的主要亚组。 CD1c(BDCA-1)...
目的 探究EV71与CA16对恒河猴CD1c+DC的感染情况,与两者感染后Ⅰ型干扰素(typeⅠinterferon,IFN-Ⅰ)产生通路中及辅助性T细胞(T helper cells,Th)分化过程中相关基因的改变.方法 本文通过采用免疫荧光、qRT-PCR、噬斑实验、流式细胞术等方法比较了EV71与CA16感染恒河猴CD1c+DC在不同的时间点内IFN-Ⅰ的产生,病毒...
Expression of IL-1β, IL-6, IL-8, IL-23, TNF-α, IFN-γ and TGF-β mRNA in CD1c+CD11b+ DCs was higher than in CD1c+CD11b- DC subset. Co-culture of autologous naive CD4+ T cells with sorted CD1c+CD11b+ DCs expressed significantly increased levels of IL-17A and RORγt ...
It has been suggested lately that some types of antigen presenting cells-myeloid dendritic (DC-1) cells can differentiate the immune response towards Th1 type immunity, whereas lymphoid cells (DC-2) can stimulate Th2 type immunity. It has been observed that neonates are deficient in Th1 response...
(a) Cells were double-stained with the indicated mAbs to assess the purity of DC suspensions. Numbers represent the percentage of cells in the respective quadrants. (b) Migrating LCs and DDCs were double-stained with anti-CD1c and the indicated mAbs. Flow cytometry profiles are from a ...
and IL-12 and instead produced high levels of the anti-inflammatory cytokine IL-10 and regulatory molecules IDO and soluble CD25. Moreover, E. coli-activated CD1c(+) DCs suppressed T-cell proliferation in an IL-10-dependent manner. Contrary to their mouse CD8(+) DC counterparts, human CD...
Dendritic cells (DC) have the unique capacities to induce primary T-cell responses. In mice, CD8 alpha+DC are specialized to cross-prime CD8(+) T cells and... G Nizzoli,J Krietsch,A Weick,... - 《Blood》 被引量: 234发表: 2013年 Post-Therapeutic Relapse of Psoriasis after CD11a Bl...
Abbreviations, CD numeration, and alternate names: DEC-205 (CD205), B220 (CD45R), PDCA-1 (plasmacytoid DC Ag-1; CD317; Bst2), Siglec H (Sialic acid-binding immunoglobulin-like lectin H), Langerin (CD207), CD141 (BDCA-3), CD1c (BDCA-1), and CD303 (BDCA-2). Dendritic cell ...
支援DC 輸入電壓 12V +/- 5% 進階技術 Intel® 遠端喚醒技術 是 Intel® HD 音效技術 是 Intel® 虛擬化技術 (VT-x) ‡ 是 安全性與可靠性 Intel® Platform Trust Technology (Intel® PTT) 是 Intel® 受信任的執行技術 ‡ 否 所有提供的資訊仍可能隨時變更,恕不另行通知。Intel...