As a result, CD19-Cre mice exhibit diminished expression levels of CD19, with potential, yet insufficiently examined, consequences in B cell activation. Here, we report significantly heightened antibody responses upon both T-dependent (NP-KLH) and T-independent (NP-Ficoll) immunizations as well ...
将iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA插入到小鼠Cd19基因中。 应用领域:Cre工具鼠,主要在B细胞中表达等区域 *使用本品系发表的文献需注明: Cd19-Cre-IRES-tdTomato mice (Cat. NO. NM-KI-200061) were purchased from Shanghai Model Organisms Center, Inc.. ...
Excision of the Frt-flanked neoR cassette from the CD19cre knock-in trIntercross of mice transgenic for Flp-recombinase with the CD19cre mouse strain leads to excision of the Frt-flanked neo R cassette from the CD19creknock-in transgene. This significantly reduces the......
Furthermore, the utility value of the CD19-iCre model was superior than that of the CD19-Cre mice regarding deletion efficiency in IL10-floxed mice. Thus, the CD19-iCre line is a valuable tool for highly efficient gene targeting specific to the B cell compartment....
eYFP expression in CD19-Cre/eYFP mice.doi:10.1371/JOURNAL.PONE.0060643.G001Demir FilizBuch ThorstenWaisman AriPLOS ONE
Furthermore, the utility value of the CD19-iCre model was superior than that of the CD19-Cre mice regarding deletion efficiency in IL10-floxed mice. Thus, the CD19-iCre line is a valuable tool for highly efficient gene targeting specific to the B cell compartment....
The defect of B cell development in CD19-Cre+PDK1flox/flox mice is caused by B cell intrinsic defects.SungGyoo, ParkMeixiao, LongJungAh, KangWooSeok, KimChoRong, LeeSinHyeog, ImIan, StricklandJan, SchulzeLuehrmannMatthew, S. Hayden