4. CD160-activating NK cell effector functions depend on the phosphatidylinositol 3-kinase recruitment.[J].Aguerre-Girr M;Polgar B;El-Costa H;Marie-Cardine A;Bensussan A;Valitutti S;Rabot M;Barakonyi A;Le-Bouteiller P,International Immunology.2007,第4期 5. Cloning of BY55, a novel Ig s...
Individual NK cells express both activating and inhibitory receptors, which together drive the specificity toward target cells. The NK cell inhibitory receptors have been classified into three groups, namely, the heterodimeric CD94/NKG2A, the Ig-like transcript (ILT) receptors, and the members of ...
中文名称:NK细胞受体BY55抗体;CD160 英文名称:CD160 别名:By55; Natural killer cell receptor BY55; BY55; CD160 antigen [Precursor]; CD160 molecule; FLJ46513; Natural killer cell receptor BY55; NK1; NK28; BY55_HUMAN. 产品介绍: CD160是一种27kda的糖蛋白,最初用单*抗体经55鉴定。其表达与外...
CD160 (also Natural killer cell receptor BY55) is a 27-30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. These include CD56DIMCD16+cytolytic NK cells, CD8+CD28-T cells, CD8+CD101+IELs, NKT cells, gammaδTCR T cells, activated...
BY55; BY55_HUMAN; CD160; CD160 antigen [Precursor]; CD160 antigen; CD160 delta Ig; CD160 molecule; CD160 transmembrane isoform; FLJ46513; Natural killer cell receptor BY55; Natural killer cell receptor; immunoglobulin superfamily member; NK1; NK28 ...
52.linmi,sessawc.antiangiogenictherapy:creatingaunique"window"ofopportunity.cancercell.2004;6(6):529-531. 53.barakonyia,等.cuttingedge:engagementofcd160byitshla-cphysiologicalligandtriggersauniquecytokineprofilesecretioninthecytotoxicperipheralbloodnkcellsubset.jimmunol.2004;173(9):5349-5354. ...
CD160 (also BY55) is a 27 kDa member of the immunoglobulin superfamily of molecules. It is expressed on select hematopoietic cell types, including CD56dimCD16+cytotoxic NK cells, CD8+CD28-effector T cells, δ/ gamma T cells, and restricted CD4+T cells. It is a receptor for HLA-C molec...
蛋白别名: CD160; CD160 antigen; CD160 transmembrane isoform; CD160-delta Ig; natural killer cell receptor; Natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member 基因别名: BY55; CD160; NK1; NK28 UniProt ID: (Human) O95971 Entrez Gene ID: (...
The binding of CD160 to both classical and non-classical MHC I enhances NK and CD8+ cytotoxic T lymphocyte functions (PMID: 25179432). CD160 is a ligand for HVEM (herpes virus entry mediator) and the binding of CD160 to HVEM inhibits T cell activity (PMID: 19426226). 实验方案 Product ...
In T lymphocytes, the HVEM and CD160 interacting in a trans manner result in a coinhibitory signal that suppresses CD4+ T cell proliferation and IFN-γ production [39]. In contrast, in NK cells, the CD160/HVEM engagement delivers costimulatory signals that boost cytokine production and promote...