CD160 is an Ig-like glycoprotein expressed by the majority of circulating natural killer cells and 纬未 T cells. Whether CD160 could regulate CD8 + T-cell functions remains unknown. In this study, we investigated the effects of CD160 on CD8 + T cells in pancreatic cancer. First, we ...
CD160 (also Natural killer cell receptor BY55) is a 27-30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. These include CD56DIMCD16+cytolytic NK cells, CD8+CD28-T cells, CD8+CD101+IELs, NKT cells, gammaδTCR T cells, activated...
The binding of CD160 to both classical and non-classical MHC I enhances NK and CD8+ cytotoxic T lymphocyte functions (PMID: 25179432). CD160 is a ligand for HVEM (herpes virus entry mediator) and the binding of CD160 to HVEM inhibits T cell activity (PMID: 19426226). 实验方案 Product ...
CD160 expression levels on CD8+ T cells have been shown to be elevated in chronic viral infections such as human immunodeficiency virus (HIV) and Epstein Barr virus (EBV) (3). In addition, when CD160 is co-expressed with the programmed cell death protein 1 (PD-1) receptor, T cell ...
Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation. ...
BY55; NK1; NK28; CD160 Antigen; Natural killer cell receptor BY55 |CD160 简介 CD160是一种27kDa的糖蛋白。它的表达与外周血NK细胞和具有细胞溶解作用的CD8 T淋巴细胞密切相关。它的cDNA序列预测是一个富含半胱氨酸、糖基磷脂酰肌醇锚定的蛋白质,有一个与KIR2DL4分子弱同源的Ig样结构域的181个氨基酸。
别名:By55; Natural killer cell receptor BY55; BY55; CD160 antigen [Precursor]; CD160 molecule; FLJ46513; Natural killer cell receptor BY55; NK1; NK28; BY55_HUMAN. 产品介绍: CD160是一种27kda的糖蛋白,最初用单*抗体经55鉴定。其表达与外周血NK细胞和CD8 T淋巴细胞具有细胞溶解活性密切相关。
In this study, we show that one such pathway, the HVEM-CD160 axis, significantly impacts CD8+ T cell regulation and thereby the incidence of cerebral malaria. Here, we show that the co-stimulatory molecule HVEM is indeed required to maintain CD8+ T effector populations during infection. ...
Description: This BY55 monoclonal antibody reacts with human CD160, a member of the immunoglobulin superfamily expressed on natural killer cells, natural killer T cells, activated and/or memory CD4 and CD8 T cells, gamma/delta T cells, and intraepithelial cells. CD160 has been reported to bind...
few NK cells and a minor subset of CD8+ T cells. Murine CD160 has been shown to bind to a wide range of classical and non classical MHC class I molecules and regulate NK cell activation. In vitro, CD3 activation of murine CD8+ T cells increases the expression of CD16...