Furthermore, the increased frequency of IL-10+CD206+CD14+M2-like macrophages and elevated level of IL-10 in BALF of SCLC patients were positively correlated with advanced tumor stage, but negatively correlated with their survival time. On the other hand, the level of supernatant IL-10 and ...
Overall, increased IL-10+CD206+CD14+M2-like macrophages were an important feature of SCLC, rather than NSCLC, and it is associated with development of SCLC. 展开 关键词: Small cell lung cancer Macrophage Monocytes Regulatory T cells IL-10 ...
Circulating CD14+CD163+CD206+ M2 Monocytes Are Increased in Patients with Early Stage of Idiopathic Membranous NephropathyTo analyze changes in peripheral blood monocytes and their clinical significance in patients with early stage of ... H Jie,M Zhang,Y Ding,... - 《Mediators of Inflammation》...
包括了单个外泌体的粒径,浓度及蛋白表达(图1A-E)。 进一步对外泌体的亚群分析,结果显示,ARDS患者的CD14+/CD81+外泌体数量明显高于未患ARDS的患者(图2A),且30天内死亡的患者的此项数据高于存活患者(图3A)。 同时,作者也检测了其他亚群外泌体与ARDS的相关性,如CD66、CD31、CD41、CD206和EpCaM。 CD14+外泌...
Thus, monocyte-derived DCs and monocyte-derived Ms that carry the C-type lectins Dendritic Cell–Specific Intercellular adhesion molecule-3–Grabbing Nonintegrin (DC-SIGN/CD209) and Mannose Receptor (MR/CD206) are productively infected by DENV (Miller et al., 2008; Navarro-Sanchez et al., ...
The immune profiling of the tasquinimod-treated tumor revealed decreased CD206+iNOS−M2-like macrophages (Supplementary Fig. S6c-e) and increased CD86+CD206− M1-like macrophages (Supplementary Fig. S6f). The gating strategy for macrophage populations is added to Supplementary Fig. S6g. These...
Pediatr Allergy Immunol 14:255–260 Lis G, Kostyk E, Sanak M, Pietrzyk JJ (2001) Molecular studies in a population of children with bronchial asthma I polymorphism in the promoter region of gene CD14. Pneumonol Alergol Pol 69:265–272 67 Marsh DG, Breazeale DR, Ghosh B, Freidhoff LR,...
THP-1 cells did not express CD206 or CD163 following incubation with PMA, M- or GM-CSF alone or in combination. Upon infection with Lm, all primary macrophages showed good survival at high multiplicities of infection whereas viability of THP-1 was severely reduced even at lower bacterial ...
背景和目的:恶性胸腔积液是一种临床上常见的恶性肿瘤并发症.目前,恶性胸腔积液的诊断存在一定的限制性,包括主观性强,敏感性差及假阳性率的存在.因此,本研究对恶性胸腔积液中的CD163+CD14+肿瘤相关巨噬细胞(tumor-associated macrophages,TAMs)进行观察,旨在寻找一种灵敏,特异性的生物标记物诊断恶性胸腔积液.方法:选取...
The group showed that CD14+CD16+ monocytes are more strongly associated with inflammation. Compared to CD14++CD16− mononuclear cells, CD14+CD16+ monocytes have a stronger ability to induce TNF and IL-6 in the process of inflammation, and upregulate the expression of inflammatory chemokine ...