CD11c-DTR-GFP tgAntigen presenting cellCervical lymph nodesExperimental autoimmune encephalomyelitisCentral nervous systemThe concept as to how the brain maintains its immune privilege has initially been based on observations that it is lacking classical lymph vessels and later, the absence of dendritic ...
目的研究CD11c+F4/80肾脏固有树突状细胞(rDC)在肾脏缺血再灌注(IR)损伤中的作用及机制。方法采用C.FVB-Tg(Itgax-DTR/GFP)57Lan/J小鼠(以下简称DTR/GFP小鼠)经不同剂量白喉毒素处理18h后,检测小鼠肾脏rDC的清除效果及小鼠体质量的变化,筛选最佳注射剂量进行后续实验。取DTR/GFP小鼠,注射白喉毒素(16ng/g体质量)18...
To examine the role of DCs in resistance to HSV-1 infection, we employed the newly generated CD11c-DTR-GFP transgenic mouse model. This model enables the selective ablation of DCs in vivo and has successfully been used to study the role of DCs in microbial immunity (40) and in the develop...
C. et al. Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells. Clin. Exp. Immunol. 141, 398–404 (2005). 44. Wuest, T. R. & Carr, D. The role of chemokines during herpes simplex virus-1 infection. Front. Biosci. 13, 4862–4872 (2008). 45. ...
for anti-PD-L1 efficacy Methods We utilized the B16-SIY melanoma model, CD11c-DTR-GFP, and CD11c-DTR-GFP/Batf3 KO bone marrow chimeras to studythe role Batf3+ DCs play ... A Ziblat,B Horton,E Higgs,... - 《Journal for Immunotherapy of Cancer》 被引量: 0发表: 2021年 加载...
方法 采用C.FVB-Tg(hgax-DTR/GFP) 57Lan/J小鼠(以下简称DTR/GFP小鼠)经不同剂量白喉毒素处理18h后,检测小鼠肾脏rDC的清除效果及小鼠体质量的变化,筛选最佳注射剂量进行后续实验.取DTR/GFP小鼠,注射白喉毒素(16 ng/g体质量)18 h后,建立IR模型,于再灌注24 h后,检测肾功能变化、肾组织病理改变、rD...
The PLOS ONE | www.plosone.org 1 August 2013 | Volume 8 | Issue 8 | e72544 The Role of CD11+ Cells in Renoprotection by MSCs CD11c-DTR B6.FVB-Tg (Itgax-DTR/green fluorescent protein [GFP]; stock number, 004509) and IL-10 knockout (KO; B6.129P2-Il10tm1Cgn/J...
目的研究CD11c+F4/80肾脏固有树突状细胞(rDC)在肾脏缺血再灌注(IR)损伤中的作用及机制。方法采用C.FVB-Tg(Itgax-DTR/GFP)57Lan/J小鼠(以下简称DTR/GFP小鼠)经不同剂量白喉毒素处理18h后,检测小鼠肾脏rDC的清除效果及小鼠体质量的变化,筛选最佳注射剂量进行后续实验。取DTR/GFP小鼠,注射白喉毒素(16ng/g体质量)...
Probst HC, Tschannen K, Odermatt B, Schwendener R, Zinkernagel RM, and Van Den Broek M. Histo- logical analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells. Clin Exp Immunol. 2005; 141; 3; 398-404. doi: 10.1111/j.1365-2249.2005.02868.x PMID: 16045728...
Notably, recent reports showed that CD11c+ cells are critically involved in the early activation of the wound healing process using a CD11c-DTR mouse for the depletion of CD11c+ cells [36]. Nevertheless, the cellular identity of these greatly increased pulpal CD11c+ cells with an arrangement ...