Cd40 Depletion On Cd11c+ Cells Worsens Diet Induced Obesity But Ameliorates Liver Inflammation During Nashdoi:10.1016/j.atherosclerosis.2019.06.005S. AartsM. ReicheM. den ToomL. BeckersE. LutgensAtherosclerosis
CD154 CD154 is also known as CD40 ligand (CD40L), is expressed on activated T cells, and is required for isotype switching. Mutations in CD40L can cause X-linked hyper-IgM syndrome. CYTOTOXIC T LYMPHOCYTE–ASSOCIATED ANTIGEN 4 (CTLA-4) Also known as CD152, CTLA-4 is upregulated by ac...
Here we examine the targeting of the model Ag OVA to potential DC targets, including CD11c, CD205, MHC class II, CD40, TLR2 and FcRII/III, using a panel of (Fab' OVA) conjugates. In vitro studies identified CD11c, CD205 and MHC class II as superior and comparably effective ...
Notably, down-regulation of CD40, CD80, CD86, MHC I, MHC II, and F4/80 in CD11b+Ly-6Chigh monocytes of DC-ablated mice was more appar- ent after JEV infection, compared to those of JEV-infected CD11c-DTR mice that were not injected with DT. In line with this result, the ...
Human TSLP promotes CD40 ligand-induced IL-12 production by myeloid dendritic cells but maintains their Th2 priming potential. Interleukin-4 (IL-4), a major T-helper type 2 (Th2) cytokine, primes dendritic cells (DCs) for IL-12 production, suggesting a negative feedback loop to pre... ...
结果用3种细胞因子体外诱导UBMC12d,可使其扩增10倍,并出现DC典型的形态特征.负载肿瘤抗原后,细胞表面可高表达MHC-I,MHC-II,CD40,CD80,CD86,CD11c和CD54.利用... 杜英,陈绍倩,黄玉敏,... - 《细胞与分子免疫学杂志》 被引量: 0发表: 2006年 腺病毒介导的HBsAg基因修饰树突状细胞抗HBV相关肝癌免疫治疗的实验...
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百度试题 题目成熟树突状细胞的表面标志有 ( 难度:3) A. MHC分子 B. CD40 C. CD1a D. CD11c E. B7 相关知识点: 试题来源: 解析 A,B,C,D,E 反馈 收藏
Furthermore, the utilization of IL15 in combination therapy with other cytokines (e.g. IL-21 or GMCSF), or co-stimulatory molecules (CD40) is a potential avenue to be explored to improve current cancer immunotherapy. In addition, our data point to the necessity of a thorough re/evaluation ...
Moreover, these DCs expressed high levels of CD40, CD80, CD86, and MHC class II molecules. Nasal delivery of plasmid FL with OVA resulted in FL expression in both mucosal inductive and effector sites and resulted in expanded activated lymphoid DCs. Thus, nasal plasmid FL prevents mucosal ...